Results 281 to 290 of about 9,492,165 (393)

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, EarlyView.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

(6) ERYTHROCYTE DISORDER IN AUTOIMMUNE DISEASES

, 1982
Tokugoro Tsunematsu
openalex   +2 more sources

Psoriasis: a mixed autoimmune and autoinflammatory disease.

Current Opinion in Immunology, 2017
Yun Liang, M. Sarkar, L. Tsoi, J. Gudjonsson   +3 more
semanticscholar   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Application of novel CAR technologies to improve treatment of autoimmune disease. [PDF]

Front Immunol
Cheever A, Kang CC, O'Neill KL, Weber KS.   +3 more
europepmc   +1 more source

Autoimmune Diseases among Pneumoconiotic Patients

, 1982
Isamu Ebihara
openalex   +2 more sources

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

Advanced Science, EarlyView.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren, Zeda Zhao, Yuqing Chao, Panting Yu, Zhoufang Mei, Bing Du, Yiyun Cheng   +6 more
wiley   +1 more source

Author Correction: B cell depletion therapies in autoimmune disease: advances and mechanistic insights. [PDF]

Nat Rev Drug Discov
Lee DSW, Rojas OL, Gommerman JL.
europepmc   +1 more source

Circulating HLA-DR (Ia) Positive T Cells and T Cell Activation by Thyroglobulin, Thyroid Microsome, and TSH-receptor in Autoimmune Thyroid Diseases

, 1987
Kazuya Zeki, Takashi Fujihira, F Shirakawa, Kenichi Watanabe, Sumiya Eto   +4 more
openalex   +2 more sources

Functional Materials Targeted Regulation of Gasdermins: From Fundamentals to Functionalities and Applications

Advanced Science, EarlyView.
Targeted regulation of pyroptosis to modulate the immune landscape is a novel design strategy for cancer immunotherapy and anti‐inflammatory treatment. Pyroptosis, as a double‐edged sword, underscores the importance of optimizing the design strategy of functional materials and appropriately activating pyroptosis for the effective treatment of diseases.
Luyao Tian, Shuo Piao, Xia Li, Lanping Guo, Luqi Huang, Wenyuan Gao   +5 more
wiley   +1 more source