Results 281 to 290 of about 885,466 (342)

Real World Outcomes of Patients with Aggressive Lymphoma and Autoimmune Disease Treated with CART. [PDF]

Cancers (Basel)
Altomare NJ, Herr MM, Nair NM, Stephens DM, Cohen JB, Epperla N, Cortese M, Bhansali R, Moyo TK, Kenkre V, Ollila T, Hess B, Fitzgerald L, Shouse G, Davis JA, Jesme C, Pelcovits A, Moreira J, Lin A, Ma S, Winter JN, Danilov A, Barta SK, Gordon LI, Romancik J, Grover NS, Karmali R, American BiTE and CART Consortium.   +27 more
europepmc   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Severe Complications Due to Biopolymers in a Patient With Autoimmune Disease: A Case Report and Review of the Literature. [PDF]

Aesthet Surg J Open Forum
Hormaza-Jaramillo A, Peñaloza Gonzalez D, Benavides-Ibarra SA, Calvache Hernandez N, Muñoz Garcia LE, Hidalgo Cardona A, Murrillo-Mera J.   +6 more
europepmc   +1 more source

Testosterone affects female CD4+ T cells in healthy individuals and autoimmune liver diseases

Lara Henze, Nico Will, Dakyung Lee, Victor H. Haas, Christian Casar, Jasper Meyer, Stephanie Stein, Franziska Mangler, Silja Steinmann, T Poch, Jenny Krause, Johannes Fuß, Johanna Schröder, Alexandra Kulle, Paul‐Martin Holterhus, Stefan Bonn, Marcus Altfeld, Samuel Huber, Ansgar W. Lohse, Dorothee Schwinge, Christoph Schramm   +20 more
openalex   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Frontiers in Genetics
Ning Zhang, Ning Zhang, Ning Zhang, Ye Zhang, Rui-Fei Yang, Min Tan, Hai-Qing Chu, Abdur Rehman, Lu-Yu Yang, Ya-Yu Li, Fahad M. Alshabrmi, Xin Zhou, Feili Xu, Shou-Ping Gong, Hui-Ling Cao   +14 more
doaj   +1 more source

MDA5 variants trade antiviral activity for protection from autoimmune disease. [PDF]

BMC Med Genomics
Wallace C, Singh R, Modis Y.
europepmc   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Hidden face of Parkinson's disease: Is it a new autoimmune disease? [PDF]

Neural Regen Res
Jo MG, Kim SH, Yun SP.
europepmc   +1 more source