Results 291 to 300 of about 9,605,298 (318)

Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease

Science, 2022
The human immune system displays substantial variation between individuals, leading to differences in susceptibility to autoimmune disease. We present single-cell RNA sequencing (scRNA-seq) data from 1,267,758 peripheral blood mononuclear cells from 982 ...
S. Yazar, José Alquicira-Hernández, Kristof Wing, A. Senabouth, M. G. Gordon, Stacey B. Andersen, Qinyi Lu, Antonia Rowson, Thomas R. P. Taylor, Linda Clarke, Katia Maccora, Christine Y. Chen, A. Cook, Chun Jimmie Ye, K. Fairfax, A. Hewitt, J. Powell   +16 more
semanticscholar   +1 more source

Safety and Efficacy of Immune Checkpoint Inhibitors in Patients With Cancer and Preexisting Autoimmune Disease: A Nationwide, Multicenter Cohort Study

Arthritis & Rheumatology, 2019
Immune checkpoint inhibitors (ICIs) for cancer therapy frequently induce immune‐related adverse effects (IRAEs). Therefore, most patients with preexisting autoimmune diseases have been excluded from clinical trials of ICIs.
A. Tison, G. Quéré, L. Miséry, E. Funck-Brentano, F. Danlos, É. Routier, C. Robert, Y. Loriot, O. Lambotte, B. Bonniaud, C. Scalbert, S. Maanaoui, T. Lesimple, S. Martinez, M. Marcq, C. Chouaid, C. Dubos, F. Brunet‐Possenti, C. Stavris, L. Chiche, N. Bénéton, S. Mansard, F. Guisier, H. Doubre, F. Skowron, F. Aubin, O. Zehou, C. Rogé, M. Lambert, A. Pham‐Ledard, M. Beylot‐Barry, R. Veillon, N. Kramkimel, D. Giacchero, J. de Quatrebarbes, C. Michel, J. Auliac, Gilles Gonzales, C. Decroisette, G. Le Garff, I. Carpiuc, H. Vallerand, E. Nowak, D. Cornec, M. Kostine   +44 more
semanticscholar   +1 more source

Type I Interferons in Autoimmune Disease.

Annual Review of Pathology, 2019
Type I interferons, which make up the first cytokine family to be described and are the essential mediators of antivirus host defense, have emerged as central elements in the immunopathology of systemic autoimmune diseases, with systemic lupus ...
M. Crow, M. Olferiev, K. Kirou
semanticscholar   +1 more source

Prevalence of autoimmune disease in women with premature ovarian failure

European journal of contraception & reproductive health care, 2019
Objective: The aim of the study was to investigate the relationship between premature ovarian failure and autoimmune disease. Methods: This interdisciplinary prospective study included 52 consecutively recruited women with premature ovarian failure, aged
B. Grossmann, S. Saur, K. Rall, A. Pecher, Stephanie Hübner, J. Henes, M. Henes   +6 more
semanticscholar   +1 more source

Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

Nature Reviews Rheumatology, 2021
D. Mauro, Ranjeny Thomas, G. Guggino, R. Lories, M. Brown, F. Ciccia   +5 more
semanticscholar   +1 more source

Onconephrology: The intersections between the kidney and cancer

Ca-A Cancer Journal for Clinicians, 2021
Mitchell H Rosner, Kenar D Jhaveri, Mark A Perazella   +2 more
exaly  

Cardio‐oncology care in the era of the coronavirus disease 2019 (COVID‐19) pandemic: An International Cardio‐Oncology Society (ICOS) statement

Ca-A Cancer Journal for Clinicians, 2020
Joerg Herrmann, Daniel J Lenihan, Joseph Carver   +2 more
exaly  

Use of Immune Checkpoint Inhibitors in the Treatment of Patients With Cancer and Preexisting Autoimmune Disease

Annals of Internal Medicine, 2018
N. Abdel-Wahab, Mohsin Shah, M. Lopez-Olivo, M. Suarez‐Almazor   +3 more
semanticscholar   +1 more source

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg, Arnav Mehta, Linda C Chu   +2 more
exaly