Results 61 to 70 of about 892,868 (364)
This study aimed to assess cardiac function using the Myocardial Performance Index (MPI) in spondyloarthritis (SpA) patients.
Alvianto Steven +6 more
doaj +1 more source
Targeting MCR-3 and membrane biosynthesis: mechanistic insights into pterostilbene-colistin synergy
Colistin is a crucial antibiotic for treating infections caused by multidrug-resistant Enterobacterales. However, the emergence of plasmid-mediated mcr genes has significantly compromised their clinical efficacy. Natural adjuvants, such as pterostilbene,
Fei Zeng +8 more
doaj +1 more source
An antigen-driven B-cell response within the salivary glands of patients with Sjögren’s syndrome [PDF]
Infection with a bacterium or virus induces the production of antibodies, specialised protein molecules that bind to and eliminate the microorganism.
Berek, C., Stott, D.I.
core
Pediatric liver diseases: current challenges and future perspectives [PDF]
Chronic liver diseases in children represent a rising problem with significant effects on public health. In fact, several pediatric liver diseases are precursors of adult chronic hepatopathies, cirrhosis and hepatocellular carcinoma.
Alisi, Anna +5 more
core +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation and joint damage. Emerging evidence highlights the role of gut and oral microbiota in RA pathogenesis, with microbial dysbiosis potentially exacerbating ...
Federica Dell’Atti +10 more
doaj +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
AKRs confer oligodendrocytes resistance to differentiation-stimulated ferroptosis
Ferroptosis is a recently characterized form of cell death that has gained attention for its roles in both pathological and physiological contexts. The existence of multiple anti-ferroptotic pathways in both neoplastic and healthy cells, along with the ...
Valentina Saverio +7 more
doaj +1 more source
The potential roles of herpesvirus and cytomegalovirus in the exacerbation of pemphigus vulgaris
Background: Among exogenous etiologies, the critical role of microbial agents such as herpesviruses (HSV1/2) and cytomegalovirus (CMV) in triggering and flaring autoimmune conditions such as pemphigus vulgaris (PV) has been recently discovered ...
Fariba Mohammadi +11 more
doaj +1 more source
Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou +31 more
core +1 more source

