Results 41 to 50 of about 548,302 (167)

Omics approaches open new horizons in major depressive disorder: from biomarkers to precision medicine

Frontiers in Psychiatry
Major depressive disorder (MDD) is a recurrent episodic mood disorder that represents the third leading cause of disability worldwide. In MDD, several factors can simultaneously contribute to its development, which complicates its diagnosis. According to
Fabiola Stolfi, Fabiola Stolfi, Hugo Abreu, Hugo Abreu, Riccardo Sinella, Riccardo Sinella, Sara Nembrini, Sara Nembrini, Sara Centonze, Sara Centonze, Virginia Landra, Claudio Brasso, Giuseppe Cappellano, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti, Annalisa Chiocchetti   +16 more
doaj   +1 more source

Autoimmunity and autoimmune disease [PDF]

Nephrology Dialysis Transplantation, 2001
Katsorida, ME, Moutsopoulos, HM
openaire   +3 more sources

Correction to: Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney

Cell & Bioscience, 2022
Hongwei Wu, Fanna Liu, Yu Shangguan, Yane Yang, Wei Shi, Wenlong Hu, Zhipeng Zeng, Nan Hu, Xinzhou Zhang, Berthold Hocher, Donge Tang, Lianghong Yin, Yong Dai   +12 more
doaj   +1 more source

FSP1 is a predictive biomarker of osteosarcoma cells’ susceptibility to ferroptotic cell death and a potential therapeutic target

Cell Death Discovery
Human osteosarcoma (OS) is a relatively rare malignancy preferentially affecting long body bones which prognosis is often poor also due to the lack of effective therapies. Clinical management of this cancer basically relies on surgical removal of primary
Elzbieta Panczyszyn, Valentina Saverio, Romina Monzani, Mara Gagliardi, Jelena Petrovic, Jasmina Stojkovska, Licio Collavin, Marco Corazzari   +7 more
doaj   +1 more source

Autoimmune Diseases in Humans, e.g. Autoimmune Rheumatic Diseases

Intervirology, 1993
In spite of increasing evidence that viruses and especially retroviruses could act as etiologic factors in autoimmune and especially autoimmune rheumatic diseases, clear-cut evidence for an involvement of these agents is still missing. Findings, which, for example, indirectly support the hypothesis that retroviruses might play a part, are the ...
J R, Kalden, M, Herrmann
openaire   +2 more sources

Functional Shifts in Gut Microbiota and Associated Metabolites Suggest Gut–Brain Axis Dysregulation in Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS)

Microorganisms
Background: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (PANDAS) are characterized by neuropsychiatric symptoms linked to immune dysregulation.
Shabana M. Shaik, Gabriele Schiro, Daniel Laubitz, Juliette C. Madan, Connor P. Kelley, Michael Daines, Sydney A. Rice, Fayez K. Ghishan, Pawel R. Kiela   +8 more
doaj   +1 more source

Unbiased autoantibody screening using nucleic acid protein programmable array in pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections

Frontiers in Behavioral Neuroscience
IntroductionPediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS) is characterized by the abrupt onset of obsessive-compulsive disorder and/or tics, along with other neuropsychiatric symptoms in children, in the
Jelena Eremija, Michael Daines, Sydney Rice, Juliette C. Madan, Juliette C. Madan, Susan Swedo, Fayez K. Ghishan, Pawel R. Kiela, Pawel R. Kiela   +8 more
doaj   +1 more source

Human cytomegalovirus infection triggers a paracrine senescence loop in renal epithelial cells

Communications Biology
Human cytomegalovirus (HCMV) is an opportunistic pathogen causing severe diseases in immunosuppressed individuals. To replicate its double-stranded DNA genome, HCMV induces profound changes in cellular homeostasis that may resemble senescence.
Stefano Raviola, Gloria Griffante, Andrea Iannucci, Shikha Chandel, Irene Lo Cigno, Davide Lacarbonara, Valeria Caneparo, Selina Pasquero, Francesco Favero, Davide Corà, Elena Trisolini, Renzo Boldorini, Vincenzo Cantaluppi, Santo Landolfo, Marisa Gariglio, Marco De Andrea   +15 more
doaj   +1 more source

Uncovering Genetic Variation in Systemic Lupus Erythematosus Risk Variants in Indigenous Peruvians

ACR Open Rheumatology
Objective Systemic lupus erythematosus (SLE) results in worse clinical outcomes among individuals of Amerindian descent. The genetic basis for this is uncertain, and there is a significant lack of genetic research focused on Amerindian ancestry ...
Cristina M. Lanata, Richard F. Oppong, Mary K. Horton, Victor Borda, Manuel F. Ugarte‐Gil, Joanne Nititham, Eduardo Tarazona‐Santos, Timothy D. O'Connor, Heinner Guio, Lindsey A. Criswell   +9 more
doaj   +1 more source

Pituitary–Adrenal Axis and Peripheral Immune Cell Profile in Long COVID

Biomedicines
In Long COVID, dysfunction in the pituitary–adrenal axis and alterations in immune cells and inflammatory status are warned against. We performed a prospective study in a cohort of 42 patients who suffered COVID-19 at least 6 months before attending the ...
Jaume Alijotas-Reig, Ariadna Anunciacion-Llunell, Enrique Esteve-Valverde, Stephanie Morales-Pérez, Sergio Rivero-Santana, Jaume Trapé, Laura González-García, Domingo Ruiz, Joana Marques-Soares, Francesc Miro-Mur   +9 more
doaj   +1 more source