Results 21 to 30 of about 892,868 (364)

Autoimmune Rheumatic Diseases [PDF]

BioMed Research International, 2014
The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Nevertheless, all these conditions share similar pathophysiological mechanisms [
Anaya, Juan Manuel, Shoenfeld, Yehuda, Buttgereit, Frank, González-Gay Mantecón, Miguel Ángel   +3 more
openaire   +5 more sources

The characteristics of extrachromosomal circular DNA in patients with end-stage renal disease

European Journal of Medical Research, 2023
Background End-stage renal disease (ESRD) is the final stage of chronic kidney disease (CKD). In addition to the structurally intact chromosome genomic DNA, there is a double-stranded circular DNA called extrachromosomal circular DNA (eccDNA), which is ...
Yue Peng, Yixi Li, Wei Zhang, Yu ShangGuan, Ting Xie, Kang Wang, Jing Qiu, Wenjun Pu, Biying Hu, Xinzhou Zhang, Lianghong Yin, Donge Tang, Yong Dai   +12 more
doaj   +1 more source

Assessment and personalised advice for fatigue in systemic lupus erythematosus using an innovative digital tool: the Lupus Expert system for the Assessment of Fatigue (LEAF) study

RMD Open, 2023
Background Fatigue is reported as the most prevalent symptom by patients with systemic lupus erythematosus (SLE). Fatigue management is complex due to its multifactorial nature.
Laurent Arnaud, Matteo Piga, Manuel Francisco Ugarte-Gil, Philippe Mertz, Luc Pijnenburg, Marina Rinagel, Lou Kawka, Juan-Camilo Sarmiento-Monroy, Sophie Geneton, Julien Blaess   +9 more
doaj   +1 more source

The Chromatin Accessibility Landscape of Peripheral Blood Mononuclear Cells in Patients With Systemic Lupus Erythematosus at Single-Cell Resolution

Frontiers in Immunology, 2021
ObjectiveSystemic lupus erythematosus (SLE) is a complex autoimmune disease, and various immune cells are involved in the initiation, progression, and regulation of SLE.
Haiyan Yu, Haiyan Yu, Xiaoping Hong, Hongwei Wu, Fengping Zheng, Zhipeng Zeng, Weier Dai, Lianghong Yin, Dongzhou Liu, Donge Tang, Yong Dai   +10 more
doaj   +1 more source

Serum thyroid hormone antibodies are frequent in patients with polyglandular autoimmune syndrome type 3, particularly in those who require thyroxine treatment [PDF]

, 2017
Polyglandular autoimmune syndrome (PAS) type 3 consists of autoimmune thyroid disease (AITD) coexisting with ≥1 non-thyroidal autoimmune disease (NTAID) other than Addison’s disease and hypoparathyroidism. We evaluated the prevalence and repertoire of
Benvenga, Salvatore, Centanni, Marco, Di Bari, Flavia, Galletti, Marina, Mandolfino, Mattia, Santaguida, MARIA GIULIA, Segni, Maria, Virili, Camilla, Vita, Roberto   +8 more
core   +1 more source

Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus

Frontiers in Immunology, 2022
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with multi-organ inflammation and defect, which is linked to many molecule mediators. Oxylipins as a class of lipid mediator have not been broadly investigated in SLE.
Jingquan He, Jingquan He, Chiyu Ma, Donge Tang, Shaoyun Zhong, Xiaofang Yuan, Fengping Zheng, Zhipeng Zeng, Yumei Chen, Dongzhou Liu, Xiaoping Hong, Weier Dai, Lianghong Yin, Yong Dai   +13 more
doaj   +1 more source

Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up [PDF]

, 2016
Primary autoimmune hemolytic anemia (P-AIHA) is a relatively uncommon and hetereogeneous disease characterized by the destruction of red blood cells due to anti-erythrocyte autoantibodies (AeAbs) in the absence of an associated disease [1–3].
ARMIENTO, DANIELE, CARONNA, Roberto, COLAFIGLI, GIOIA, Coluzzi, S, De Propris, Ms, FERRETTI, ANTONIETTA, FOA, Roberto, GIOVANNETTI, GIANLUCA, GIRELLI, Gabriella, GUARINI, Anna, LA ROCCA, URSULA, MAURO, Francesca Romana, MOLICA, MATTEO, Morano, G, Paoloni, F, Trastulli, F   +15 more
core   +1 more source

Letter to the editor: autoimmune pathogenic mechanisms in Huntington’s disease [PDF]

, 2018
Letter to the Editor: Autoimmune pathogenic mechanisms in Huntington's ...
DE VINCENTIIS, Marco, De Virgilio, A, Fusconi, M, GRECO, Antonio, Inghilleri, M, Ralli, M   +5 more
core   +1 more source

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce, D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, DE VIRGILIO, ARMANDO, DI STADIO, Arianna, GRECO, Antonio, LONGO, Lucia, RALLI, MASSIMO   +7 more
core   +1 more source

Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]

, 1994
By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Baekkeskov S., Banga J. P., Bernhard O. Boehm, Betterle C. F., Bjork E., Bottazzo G. F, Bottazzo G. F., Christie M. R., Genovese S., Hagopan W. A., Jochen Seissler, Karlsen A. E., Kawasaki E., Kim J., Ludwig Mauch, Mauch L., Muir A., Nadja Yassin, Richter W., Riley W. J., Sabine Bieg, Scherbaum W. A, Scherbaum W. A., Schmidli R TS, Seissler J., Solimena M., Tarn A. C., Ujihara N., Velloso L. A., Wagner R., Wagner R., Werner A. Scherbaum, Wolfgang Northemann   +32 more
core   +1 more source