Results 21 to 30 of about 548,302 (167)

MicroRNA in autoimmunity and autoimmune diseases

Journal of Autoimmunity, 2009
MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery, Diagnostic Sciences, University of Florida, Gainesville, FL, USA ( host institution ), Pauley, Kaleb M., Cha, Seunghee, Chan, Edward K.L.   +4 more
openaire   +4 more sources

The Gut-Ex-Vivo System (GEVS) Is a Dynamic and Versatile Tool for the Study of DNBS-Induced IBD in BALB/C and C57BL/6 Mice, Highlighting the Protective Role of Probiotics

Biology, 2022
Background: IBD is a spectrum of pathologies characterized by dysregulated immune activation leading to uncontrolled response against the intestine, thus resulting in chronic gut inflammation and tissue damage.
Romina Monzani, Mara Gagliardi, Nausicaa Clemente, Valentina Saverio, Elżbieta Pańczyszyn, Claudio Santoro, Nissan Yissachar, Annalisa Visciglia, Marco Pane, Angela Amoruso, Marco Corazzari   +10 more
doaj   +1 more source

The occurrence of Adrenocorticotropic hormone-independent Cushing's syndrome in a woman with the history of papillary thyroid carcinoma: a case report

Journal of Medical Case Reports, 2021
Background Thyroid papillary carcinoma is one of the most common endocrine tumors, and it accounts for 85% of thyroid tumors. Adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome is a rare disease. In this case report, we discuss a very rare
Mashallah Tabatabaizadeh, Sara Hasibi Taheri, Mohammad Eydi, Mohammad Shayestehpour   +3 more
doaj   +1 more source

Advances in antigens associated with Idiopathic Membranous Nephropathy

Journal of the Formosan Medical Association, 2021
Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Idiopathic MN (IMN), one of the forms of MN, usually has an unknown etiology. IMN is described as an autoimmune disease, and its pathogenesis is quite complex.
Shan-Shan Li, Dong-E Tang, Yong Dai
doaj   +1 more source

Autoimmune Thyroid Disease [PDF]

Endocrine, 2004
Abstract Along with neoplasia, autoimmunity is the most common cause of endocrine disease, and of this group of disorders, thyroid autoimmunity is the most frequent. Conversely, the autoimmune thyroid diseases are the most common organ-specific or non-organ-specific autoimmune conditions affecting any site.
openaire   +3 more sources

Using two-step cluster analysis to classify inpatients with primary biliary cholangitis based on autoantibodies: A real-world retrospective study of 537 patients in China

Frontiers in Immunology, 2023
BackgroundA variety of autoantibodies have been detected in primary biliary cholangitis (PBC), while the presence of autoantibody clusters and their clinical significance have not been fully understood.
Dan-Tong Zhao, Hui-Ping Yan, Hui-Ping Yan, Hui-Yu Liao, Yan-Min Liu, Ying Han, Hai-Ping Zhang, Wei-Ming Zhang, Chun-Yang Huang, Xiu-Hong Liu, Jin-Li Lou, Yan Zhao, Yan Zhao   +12 more
doaj   +1 more source

Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells

Hereditas, 2021
Background Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities.
Chunhong Li, Yu Shangguan, Peng Zhu, Weier Dai, Donge Tang, Minglin Ou, Yong Dai   +6 more
doaj   +1 more source

Quality of life in mild and severe alopecia areata patients

International Journal of Women's Dermatology, 2018
Background: Alopecia areata is a relapsing hair disorder characterized by a sudden hairloss and has a considerable impact on patient’s quality of life. The goal of this study was to determine quality of life among patients with mild and severe forms of ...
Robabeh Abedini, Zahra Hallaji, Vahideh Lajevardi, Maryam Nasimi, Mona Karimi Khaledi, Hamid Reza Tohidinik   +5 more
doaj   +1 more source

Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading

Frontiers in Immunology, 2017
Evidence for original antigenic sin in spontaneous thyroid autoimmunity is revealed by autoantibody interactions with immunodominant regions on thyroid autoantigens, thyroglobulin (Tg), thyroid peroxidase (TPO), and the thyrotropin receptor (TSHR) A ...
Sandra M. McLachlan, Basil Rapoport
doaj   +1 more source

Myocardial performance index to assess cardiac function in spondyloarthritis: A systematic review and meta-analysis

Romanian Journal of Internal Medicine
This study aimed to assess cardiac function using the Myocardial Performance Index (MPI) in spondyloarthritis (SpA) patients.
Alvianto Steven, Parlindungan Faisal, Dalimunthe Naomi Niari, Widjanarko Nicolas Daniel, Gotama Yovita, Kultsum Ummi, Efendi Cristopher   +6 more
doaj   +1 more source