Results 21 to 30 of about 5,515,723 (295)
Rat models of autoimmune uveitis [PDF]
, 2008 Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Wildner, Gerhild +2 more
core +1 more source
Non-coronary cardiac manifestations of systemic lupus erythematosus in adults: a comparative study
The Pan African Medical Journal, 2019 Cardiac manifestations develop in the majority of patients with systemic lupus erythematosus (SLE) at some time during the course of their disease.
Sameh Sayhi +7 more
doaj +1 more source
Association between Antibodies to the MR 67,000 Isoform of Glutamate Decarboxylase (GAD) and Type 1 (Insulin-Dependent) Diabetes Mellitus with Coexisting Autoimmune Polyendocrine Syndrome Type II [PDF]
, 1994 By using an immunoprecipitation assay, we analysed reactivity of autoantibodies to human recombinant GAD65 and GAD67 in sera from patients with autoimmune polyendocrine syndrome Type II (APS II) with and without Type 1 (insulin-dependent) diabetes ...
Seißler, Jochen +6 more
core +1 more source
Innate immune activation in experimental autoimmune myocarditis [PDF]
, 2007 Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core +1 more source
Epigenetics and Autoimmune Diseases [PDF]
Autoimmune Diseases, 2012 Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone modification, nucleosome positioning, and microRNAs (miRNAs) are essential to carry out key functions in the regulation of gene ...
Paula Quintero-Ronderos +1 more
openaire +3 more sources
Frontiers in Oncology, 2022 As recently reported by The International Agency for Research on Cancer (IARC), breast cancer has the highest incidence of all cancers in 2020. Many studies have revealed that golgi apparatus is closely associated with the development of breast cancer ...
Junping Liu +10 more
doaj +1 more source
MicroRNA in autoimmunity and autoimmune diseases
Journal of Autoimmunity, 2009 MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery +4 more
openaire +4 more sources
Biomedicines, 2023 Antiphospholipid antibodies (APLA) are strongly associated with thrombosis seen in patients with antiphospholipid syndrome. In COVID-19, thrombosis has been observed as one of the main comorbidities.
Jaume Alijotas-Reig +5 more
doaj +1 more source
Biology, 2022 Background: IBD is a spectrum of pathologies characterized by dysregulated immune activation leading to uncontrolled response against the intestine, thus resulting in chronic gut inflammation and tissue damage.
Romina Monzani +10 more
doaj +1 more source
Journal of Medical Case Reports, 2021 Background Thyroid papillary carcinoma is one of the most common endocrine tumors, and it accounts for 85% of thyroid tumors. Adrenocorticotropic hormone (ACTH)-independent Cushing's syndrome is a rare disease. In this case report, we discuss a very rare
Mashallah Tabatabaizadeh +3 more
doaj +1 more source