Results 141 to 150 of about 9,729,229 (308)

Predictors of mortality in hospitalised patients with COVID-19: a 1-year case–control study

open access: yesBMJ Open
Background A paucity of predictive models assessing risk factors for COVID-19 mortality that extend beyond age and gender in Latino population is evident in the current academic literature.Objectives To determine the associated factors with mortality, in
Juan-Manuel Anaya   +17 more
doaj   +1 more source

Disease Trajectory Maps [PDF]

open access: yesarXiv, 2016
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differences in the way these diseases ...
arxiv  

B cell reductive therapy with rituximab in the treatment of rheumatoid arthritis. [PDF]

open access: yes, 2009
The approach to treating autoimmune disorders is currently undergoing a significant change in focus. As therapies are developed that are more precise in targeting the pathogenesis for these diseases, patients experience significantly fewer side effects ...
Sands, Jacob, Tuscano, Joseph M
core   +2 more sources

Evidence for C1q-mediated crosslinking of CD33/LAIR-1 inhibitory immunoreceptors and biological control of CD33/LAIR-1 expression

open access: yesScientific Reports, 2017
C1q collagen-like region (CLR) engaging and activating the LAIR-1 inhibitory immunoreceptor represents a non-complement mechanism for maintaining immune quiescence.
Myoungsun Son   +5 more
doaj   +1 more source

Prediction of Alzheimer's disease-associated genes by integration of GWAS summary data and expression data [PDF]

open access: yesarXiv, 2018
Alzheimer's disease is the most common cause of dementia. It is the fifth-leading cause of death among elderly people. With high genetic heritability (79%), finding disease causal genes is a crucial step in find treatment for AD. Following the International Genomics of Alzheimer's Project (IGAP), many disease-associated genes have been identified ...
arxiv  

Leaky Gut As a Danger Signal for Autoimmune Diseases

open access: yesFrontiers in Immunology, 2017
The intestinal epithelial lining, together with factors secreted from it, forms a barrier that separates the host from the environment. In pathologic conditions, the permeability of the epithelial lining may be compromised allowing the passage of toxins,
Qinghui Mu   +3 more
semanticscholar   +1 more source

Autoantibody status in systemic sclerosis patients defines both cancer risk and survival with ANA negativity in cases with concomitant cancer having a worse survival

open access: yesOncoImmunology, 2019
Background: A higher rate of cancer in systemic sclerosis (SSc) is recognized but the role of SSc-linked autoantibodies status (positive/negative and autoantibody specificities) in the survival of SSc-patients with cancer remains poorly understood ...
Abdulla Watad   +7 more
doaj   +1 more source

Going Beyond H&E and Oncology: How Do Histopathology Foundation Models Perform for Multi-stain IHC and Immunology? [PDF]

open access: yesarXiv
This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including ImageNet-pretrained networks, and histopathology foundation models trained on both public and proprietary data, on ...
arxiv  

Home - About - Disclaimer - Privacy