Results 141 to 150 of about 767,890 (335)

Acute Myeloid Leukemia: A Key Role of DGKα and DGKζ in Cell Viability

Cells
Acute myeloid leukemia (AML) is a heterogeneous disease with an unmet need for novel therapeutic drugs. Previous studies have reported the upregulation of diacylglycerol kinases (DGKs) in AML.
Elisa Gorla, Marco Cristiano Cartella, Edoardo Borghetti, Ginevra Lovati, Luisa Racca, Teresa Gravina, Giorgio Biazzo, Gabriele Bonello, Valeria Malacarne, Veronica De Giorgis, Davide Corà, Marcello Manfredi, Alberto Massarotti, Andrea Graziani, Gianluca Baldanzi   +14 more
doaj   +1 more source

Accuracy of diagnostic codes and algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in administrative claims and electronic health records: systematic review and meta‐analysis.

Arthritis Care &Research, Accepted Article.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in electronic health records (EHRs). Methods We searched MEDLINE, Embase, and CENTRAL databases and included studies that validated case definitions against a reference standard such ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Eating Disorders, Autoimmune, and Autoinflammatory Disease

, 2017
Stephanie Zerwas, Janne Tidselbak Larsen, Liselotte Petersen, Laura M. Thornton, Michela Quaranta, Susanne Vinkel Koch, David S. Pisetsky, Preben Bo Mortensen, Cynthia M. Bulik   +8 more
openalex   +2 more sources

Rapid and reversible responses to IVIG in autoimmune neuromuscular diseases suggest mechanisms of action involving competition with functionally important autoantibodies [PDF]

, 2013
Melvin Berger, Daniel E. McCallus, Cindy Lin   +2 more
openalex   +1 more source

Patient-derived Fab structures suggest mechanism by which affinity maturation promotes autoantibody recognition of MuSK in the autoimmune disease myasthenia gravis [PDF]

, 2020
Casey Vieni, Miriam L. Fichtner, Rachel L. Redler, Ljuvica Kolich, Steven J. Burden, Kevin C. O’Connor, Damian C. Ekiert   +6 more
openalex   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

CARD9 mediates dendritic cell–induced development of Lyn deficiency–associated autoimmune and inflammatory diseases

, 2019
Jun Ma, Clare L. Abram, Yongmei Hu, Clifford A. Lowell   +3 more
openalex   +2 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Piperine suppresses M1 phenotype and induces indoleamine 2,3-dioxygenase gene in LPS-stimulated murine macrophage cell line

BMC Research Notes
Objective Activated macrophages play important roles during immune responses by polarizing into M1 and M2 subsets and overproducing several mediators such as nitric oxide (NO), pro- and anti-inflammatory cytokines, and indoleamine 2,3-dioxygenase (IDO ...
Nasser Gholijani, Zeinab Dehghan, Samira Sadat Abolmaali, Atefe Ghamar Talepoor, Kurosh Kalantar, Gholamreza Daryabor   +5 more
doaj   +1 more source

Non-Antibody-Secreting Functions of B Cells and Their Contribution to Autoimmune Disease

, 2019
Andrew Getahun, John C. Cambier
openalex   +2 more sources