Results 171 to 180 of about 9,455,042 (324)

Outcome of pregnancy in patients with autoimmune rheumatic disease before the disease onset. [PDF]

, 1988
A. Siamopoulou‐Mavridou, M. N. Manoussakis, Anestis Mavridis, Haralampos Μ. Moutsopoulos   +3 more
openalex   +1 more source

hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation

Advanced Science, EarlyView.
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang, Chenyan Huang, Lei Sun, Lyu Zhou, Yudi Niu, Kaini Liang, Bingjie Wu, Peng Zhao, Zhiqiang Liu, Xiaolin Zhou, Peng Zhang, Jianchen Wu, Jie Na, Yanan Du   +13 more
wiley   +1 more source

Exploring the Generalization of Cancer Clinical Trial Eligibility Classifiers Across Diseases [PDF]

arXiv
Clinical trials are pivotal in medical research, and NLP can enhance their success, with application in recruitment. This study aims to evaluate the generalizability of eligibility classification across a broad spectrum of clinical trials. Starting with phase 3 cancer trials, annotated with seven eligibility exclusions, then to determine how well ...
arxiv  

(1) THE AUTOIMMUNE DISEASE FROM THE VIEWPOINT OF GERMFREE ANIMAL RESEARCH

, 1967
Masasumi Miyakawa
openalex   +2 more sources

Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases [PDF]

, 1985
Barbara Czarnocka, Jean Ruf, Mireille Ferrand, Pierre Carayon, Serge Lissitzky   +4 more
openalex   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

Cytokines and Inflammatory Mediators in Systemic Lupus Erythematosus

European Medical Journal Rheumatology, 2018
Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by a breakdown in immune tolerance that induces an attack on normal tissues by the immune system.
Manuel Rojas, Yhojan Rodríguez, Kelly Joan Leon, Yovana Pacheco, Yeny Acosta-Ampudia, Diana M. Monsalve, Carolina Ramírez-Santana, Juan-Manuel Anaya   +7 more
doaj  

From Psoriasis to Psoriatic Arthritis: Decoding the Impact of Treatment Modalities on the Prevention of Psoriatic Arthritis

Rheumatology and Therapy
Introduction Biologic therapies are licensed for both psoriasis (PsO) and psoriatic arthritis (PsA) with some electronic medical record data suggest that IL (Interleukin)-23 blockers might be more protective in PsA prevention than TNF blockers; however ...
Abdulla Watad, Alen Zabotti, Yonatan Shneor Patt, Omer Gendelman, Arad Dotan, Niv Ben-Shabat, Lior Fisher, Dennis McGonagle, Howard Amital   +8 more
doaj   +1 more source

Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. [PDF]

, 1980
A D Steinberg, J B Roths, Edwin D. Murphy, Robert T. Steinberg, E S Raveche   +4 more
openalex   +1 more source

YC‐4‐3, a Novel Glycogen Synthase Kinase 3β Inhibitor, Alleviates the Endoplasmic Reticulum Stress of Macrophages in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
A patented GSK‐3β inhibitor (GSK‐3βi), new benzothiazepinone compounds (BTZs), YC‐4‐3, can modulate the inflammatory status of macrophages in primary immune thrombocytopenia (ITP), and improve the thrombocytopenia in murine ITP models by directly interacting with endoplasmic reticulum (ER) stress response.
Pengcheng Xu, Lili Ji, Yanxia Zhan, Yang Ou, Xia Shao, Xibing Zhuang, Fanli Hua, Feng Li, Hao Chen, Yong Chu, Yunfeng Cheng   +10 more
wiley   +1 more source