Results 181 to 190 of about 9,455,042 (324)

Intrathyroidal T Cell Clones from Patients with Autoimmune Thyroid Disease* [PDF]

, 1987
Wilma MacKenzie, Arthur E. Schwartz, Eugene Friedman, Terry F. Davies   +3 more
openalex   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Current status of liver transplantation for non‐B non‐C liver cirrhosis and hepatocellular carcinoma

Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 42-52, January 2023., 2023
Recently, the cases of LT for non‐B non‐C cirrhosis and HCC have been increasing in Japan as well as worldwide. Perioperative management of non‐B non‐C liver disease is problematic due to various risk factors, including alcohol consumption and metabolic syndrome‐related risks, such as obesity and diabetes mellitus.
Takahiro Nishio, Takashi Ito, Koichiro Hata, Kojiro Taura, Etsuro Hatano   +4 more
wiley   +1 more source

Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA

Advanced Science, EarlyView.
In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa, Rikako Sato, Mariko Konaka, Yuma Yamada, Hideyoshi Harashima, Yusuke Sato   +5 more
wiley   +1 more source

Desmoglein ELISA in the Diagnosis of Pemphigus and Its Correlation with the Severity of Pemphigus Vulgaris

Iranian Journal of Allergy, Asthma and Immunology, 2009
Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Mortazavi Hossein, Shahdi Majid , Amirzargar Ali Akbar , S.Naraghi Zahra, Valikhani Mahin , Daneshpazhooh Maryam, Vasheghani-Farahani Amir, Sedaghat Mojtaba, Chams-Davatchi Cheyda   +8 more
doaj  

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

Advanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang, Xin Zhang, Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang   +17 more
wiley   +1 more source

Sensorimotor Perineuritis – An Autoimmune Disease? [PDF]

, 1985
Christopher N. Bourque, Brian A. Anderson, C. Martin del Campo, Anders A. F. Sima   +3 more
openalex   +1 more source

Extravasation of Borrelia burgdorferi Across the Blood–Brain Barrier is an Extremely Rare Event

Advanced Science, EarlyView.
Lyme disease is caused by vascular dissemination of the bacteria Borrelia. In a 3D tissue‐engineered microvessel model, Borrelia extravasation across the blood–brain barrier is extremely rare, implying that neuroborreliosis is not caused via direct cytotoxicity.
Linus Wang, Zikai Xia, Anjan Singh, Bhavna Murarka, Nicole Baumgarth, John N. Aucott, Peter C. Searson   +6 more
wiley   +1 more source

Molecular Cloning and Partial Characterization of a New Autoimmune Thyroid Disease-Related Antigen* [PDF]

, 1987
Hideshi Hirayu, Pui Seto, Ronald P. Magnusson, S. Filetti, B Rapoport   +4 more
openalex   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

Advanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han, Rui Hong, Cong Cao, Wanhua Feng, Wei Zhuang, Gui Wang, Jingchao Tang, Ya Yang, Chu Zhang, Aihua Zhou, Xuebin Qu   +10 more
wiley   +1 more source