Results 11 to 20 of about 540,208 (312)

Epigenetics and autoimmune diseases [PDF]

Autoimmune Diseases, 2012
Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA.
Montoya-Ortiz, Gladis, Quintero-Ronderos, Paula   +1 more
core   +4 more sources

Autoimmune Rheumatic Diseases [PDF]

BioMed Research International, 2014
The term autoimmune rheumatic diseases (ARDs) encompasses a heterogeneous group of conditions characterized by joint involvement along with a wide spectrum of systemic manifestations. The most common ARDs are rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Nevertheless, all these conditions share similar pathophysiological mechanisms [
Anaya, Juan Manuel, Shoenfeld, Yehuda, Buttgereit, Frank, González-Gay Mantecón, Miguel Ángel   +3 more
openaire   +5 more sources

Immunogenicity and safety of the BBIBP‐CorV vaccine in patients with autoimmune inflammatory rheumatic diseases undergoing immunosuppressive therapy in a monocentric cohort

Immunity, Inflammation and Disease, 2023
Introduction Vaccination plays a fundamental role in mastering the COVID‐19 pandemic and protecting vulnerable groups. Persons with autoimmune inflammatory rheumatic diseases (AIIRD) requiring immunosuppressive therapies are prioritized for vaccination ...
Batool Zamani, Amin Moradi Hasan‐Abad, Ahmad Piroozmand, Mahsa Dehghani, Maryam Arfaatabar, Hossein Motedayyen   +5 more
doaj   +1 more source

Combination therapy for management of pemphigus patients with unexpected therapeutic response to rituximab: A report of five cases

Clinical Case Reports, 2023
Key Clinical Message The immunosuppressant agents should be considered earlier in the course of treatment with rituximab, possibly after the unfavorable response at first cycle of treatment, especially in male patients and those with high BMI.
Zeinab Aryanian, Insha Zainab Riyaz, Kamran Balighi, Ali Ahmadzade, Hamid Reza Mahmoudi, Arghavan Azizpour, Parvaneh Hatami   +6 more
doaj   +1 more source

Pervasive Sharing of Genetic Effects in Autoimmune Disease [PDF]

, 2011
Genome-wide association (GWA) studies have identified numerous, replicable, genetic associations between common single nucleotide polymorphisms (SNPs) and risk of common autoimmune and inflammatory (immune-mediated) diseases, some of which are shared ...
Klareskog, Lars, Benjamin F Voight, Worthington, Jane, Abecasis, Gonçalo R., David A van Heel, Judy Cho, Klareskog Lars, AbecasisGonç, Gonçalo R., Graham Robert R., van Heel, David A., Hansen, Kasper Lage, Graham, Robert R., Lage, Kasper, David A. van Heel, Hafler, David A., Benjamin M. Neale, Gregersen, Peter K., Gregersen, Peter, James T. Elder, Behrens Timothy, David A. Hafler, Siminovitch, Katherine A., null null, Philip L De Jager, Wijmenga, Cisca, Elizabeth Rossin, Cisca Wijmenga, David A Hafler, Chris Cotsapas, Siminovitch, KA, Kasper Lage, Mark J. Daly, Elder James T., Wallace Chris, John A. Todd, Hafler, DA, Rossin Elizabeth, Cotsapas, C, Gregersen Peter, Cotsapas, Chris, Klareskog, L, John A Todd, Behrens, Timothy, Rich Stephen S., Rich, Stephen S., Timothy Behrens, Todd, JA, Heel, David A. van, Abecasis Gonçalo R., Philip L. De Jager, Wallace, C, Neale, BM, Voight, BF, Voight, Benjamin F., Gonçalo R. Abecasis, Robert R. Graham, De Jager Philip L., Jeffrey C Barrett, Neale Benjamin M., Siminovitch Katherine A., Chris Wallace, Katherine A. Siminovitch, Benjamin M Neale, Robert R Graham, Cho, Judy, Jager, Philip L. De, Barrett Jeffrey C., Daly Mark J., Cotsapas Chris, Gonçalo R Abecasis, Rich, SS, van Heel David A., Wijmenga Cisca, Rossin, E, Graham, RR, Worthington, J, Gregersen, P, Barrett, Jeffrey C., Elder, James T., Jeffrey C. Barrett, Peter Gregersen, Katherine A Siminovitch, Lage Kasper, Wijmenga, C, Neale, Benjamin M., Wallace, Chris, Hafler David A., Behrens, T, James T Elder, Mark J Daly, Todd John A., Abecasis, GR, Elder, JT, Wijmenga, Cisca; id_orcid, Lars Klareskog, De Jager, PL, Voight Benjamin F., Benjamin F. Voight, FOCiS Network Consortia, Jane Worthington, Stephen S. Rich, Cho, J, FOCiS Network of Consortia, Cho Judy, Stephen S Rich, Barrett, JC, van Heel, DA, Todd, John A., Daly, Mark J., Daly, MJ, Worthington Jane, Rossin, Elizabeth, Lage, K, De Jager, Philip L.   +113 more
core   +1 more source

Haematopoietic stem cell transplantation for severe autoimmune diseases in children: A review of current literature, registry activity and future directions on behalf of the autoimmune diseases and paediatric diseases working parties of the European Society for Blood and Marrow Transplantation [PDF]

, 2022
Although modern clinical management strategies have improved the outcome of paediatric patients with severe autoimmune and inflammatory diseases over recent decades, a proportion will experience ongoing or recurrent/relapsing disease activity despite ...
The EBMT Autoimmune Diseases (ADWP) and Paediatric Diseases (PDWP) Working Parties
core   +2 more sources

Immunomodulation of RA Patients’ PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens

Mediators of Inflammation, 2017
Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral ...
Smadar Gertel, Gidon Karmon, Sivan Vainer, Ora Shovman, Martin Cornillet, Guy Serre, Yehuda Shoenfeld, Howard Amital   +7 more
doaj   +1 more source

Two asymptomatic facial erythematous macules in an adult male

Skin Health and Disease, 2023
Pemphigus is a group of autoimmune bullous disorders with different types. Pemphigus foliaceous (PF) is a difficult‐to‐diagnosis disorder which shares clinical features with many dermatoses.
Kamran Balighi, Kambiz Kamyab‐hesari, Parvaneh Hatami, Zeinab Aryanian   +3 more
doaj   +1 more source

Clinical Characteristics and Treatment Outcomes of Scleromyxedema: A 10-Year Retrospective Survey

Case Reports in Dermatology, 2022
Scleromyxedema is a rare but important mucinosis disorder of the skin that is presented with dermatological manifestations such as waxy papules, diffuse induration, and nondermatologic involvements like neurological and renal disorders.
Abtin Ansari, Zohre Erfani, Maryam Daneshpazhooh, Leila Mahmoudi, Zahra Saffarian, Kambiz Kamyab, Hamidreza Mahmoudi   +6 more
doaj   +1 more source

Autoimmunity and Otolaryngology Diseases [PDF]

Journal of Immunology Research, 2018
Many systemic autoimmune diseases have otolaryngology manifestations that could represent a diagnostic challenge for clinicians, as they often constitute an early sign of an otherwise asymptomatic autoimmune condition and may lead to delayed diagnosis and treatment.
Massimo Ralli, Arianna Di Stadio, Armando De Virgilio, Adelchi Croce, Marco de Vincentiis   +4 more
openaire   +6 more sources