Results 231 to 240 of about 9,455,042 (324)

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

Advanced Science, EarlyView.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

Targeting the Neonatal Fc Receptor in Autoimmune Diseases: Pipeline and Progress. [PDF]

BioDrugs
Gjølberg TT, Mester S, Calamera G, Telstad JS, Sandlie I, Andersen JT.   +5 more
europepmc   +1 more source

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. [PDF]

, 1994
Michael K. Racke, Adriana Bonomo, Dorothy E. Scott, B. Cannella, Arthur S. Levine, Cedric S. Raine, Ethan M. Shevach, Martin Röcken   +7 more
openalex   +1 more source

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Advanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou   +4 more
wiley   +1 more source

T-regulatory cells for the treatment of autoimmune diseases. [PDF]

Front Immunol
Fisher MS, Sennikov SV.
europepmc   +1 more source

Self-limited autoimmune disease related to transient donor B cell activation in mice neonatally injected with semi-allogeneic F₁ cells [PDF]

, 1992
Marcial de la Hera, Antonio de la Hera, A Ramos, Luis Buelta, José Luís Alonso, Vicente Rodríguez‐Valverde, Jesús Merino   +6 more
openalex   +1 more source

Bioorthogonal Reaction of o‐Quinone with Furan‐2(3H)‐One for Site‐Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes

Advanced Science, EarlyView.
A site‐selective, efficient, and mild tyrosine conjugation via tyrosinase oxidation and nucleophilic addition, allowing for site‐selective functionalization of peptides, recombinant proteins, and IgGs. Site‐selective mono‐functionalization of IgGs at Y296 enables the construction of immunoliposomes.
Hongfei Chen, Zhiyi Xu, Yishu Bao, Farshad Shiri, Dingdong Yuan, Yuke Hu, Biquan Li, Bin Zeng, Xiaojing Li, Hao Kong, Zikang Wang, Wilson Chun‐Yu Lau, Zhenyang Lin, Jiang Xia   +13 more
wiley   +1 more source

Airborne culprits: A comprehensive review of PM, silica, and TCDD in autoimmune diseases

Journal of Translational Autoimmunity
Autoimmune diseases (ADs) are immunological disorders arising from the breakdown of immune tolerance, influenced by various internal and external factors.
Daniel Galeano-Sánchez, Victoria Morales-González, Diana M. Monsalve, Carolina Ramırez-Santana, Yeny Acosta-Ampudia   +4 more
doaj  

Proceedings of the 1st Symposium "Autoimmune Diseases: Clinical Unmet Needs in Systemic Autoimmune Diseases Guide Clinical, Translational and Basic Research". [PDF]

Mediterr J Rheumatol
Chatzis L, Koutsogianni A, Palla P, Palamidas D, Panagopoulos P, Maria P, Andreakos E, Tzioufas AG.   +7 more
europepmc   +1 more source

LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells

Advanced Science, EarlyView.
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang, Yunjun Li, Di Han, Kun Deng, Wei Gao, Minghua Wu   +5 more
wiley   +1 more source