Results 301 to 310 of about 767,890 (335)
Some of the next articles are maybe not open access.
Infection, autoimmunity and autoimmune disease
1996Studies of the immune response of mammals to infectious agents have revealed that members of the hsp60 and hsp 70 family are highly immunodominant. Given their high conservation during evolution this was surprising, because of the apparent risk of triggering of autoimmunity and autoimmune disease during the defense of a mammal against infection ...
U, Feige, W, van Eden
openaire +2 more sources
Annual Review of Medicine, 1986
The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
openaire +2 more sources
The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
openaire +2 more sources
La Presse Médicale, 2012
Addison's disease is a rare autoimmune disorder. In the developed world, autoimmune adrenalitis is the commonest cause of primary adrenal insufficiency, where the majority of patients have circulating antibodies against the key steroidogenic enzyme 21-hydroxylase.
Catherine, Napier, Simon H S, Pearce
openaire +2 more sources
Addison's disease is a rare autoimmune disorder. In the developed world, autoimmune adrenalitis is the commonest cause of primary adrenal insufficiency, where the majority of patients have circulating antibodies against the key steroidogenic enzyme 21-hydroxylase.
Catherine, Napier, Simon H S, Pearce
openaire +2 more sources
1985
Publisher Summary This chapter discusses autoimmune endocrine disease. Many different definitions of autoimmune disease exist. From a pathophysiological point of view, autoimmune disease represents altered physiology as a direct result of antibodies or lymphocytes reacting with self antigens.
J B, Buse, G S, Eisenbarth
openaire +2 more sources
Publisher Summary This chapter discusses autoimmune endocrine disease. Many different definitions of autoimmune disease exist. From a pathophysiological point of view, autoimmune disease represents altered physiology as a direct result of antibodies or lymphocytes reacting with self antigens.
J B, Buse, G S, Eisenbarth
openaire +2 more sources
Clinics in Laboratory Medicine, 1993
A considerable proportion of the thyroid diseases is due to aberrant immune reactions toward thyroid antigens. Autoreactivity is considered to be a normal process controlled by several suppressor mechanisms. Malfunction of these suppressor mechanisms may result in autoimmune disease.
P, Mooij, H A, Drexhage
openaire +2 more sources
A considerable proportion of the thyroid diseases is due to aberrant immune reactions toward thyroid antigens. Autoreactivity is considered to be a normal process controlled by several suppressor mechanisms. Malfunction of these suppressor mechanisms may result in autoimmune disease.
P, Mooij, H A, Drexhage
openaire +2 more sources
2010
Under the term "autoimmune diseases" are comprised a large number of disorders with variable clinical expression which have in common an autoimmune pathogenesis as defined by direct, indirect or circumstantial evidence. Autoimmune diseases may affect a single organ or may determine a multisystem involvement, and most of them cause significant and ...
Arrigo, Schieppati, Erica, Daina
openaire +2 more sources
Under the term "autoimmune diseases" are comprised a large number of disorders with variable clinical expression which have in common an autoimmune pathogenesis as defined by direct, indirect or circumstantial evidence. Autoimmune diseases may affect a single organ or may determine a multisystem involvement, and most of them cause significant and ...
Arrigo, Schieppati, Erica, Daina
openaire +2 more sources
Current Opinion in Immunology, 2002
The immune system can attack almost any given organ in a very specific and directed fashion. The endocrine system appears to be particularly vulnerable to this kind of insult. Which endocrine organs are most susceptible and why? Genetic studies and animal models have revealed some commonalities for these diseases.
openaire +2 more sources
The immune system can attack almost any given organ in a very specific and directed fashion. The endocrine system appears to be particularly vulnerable to this kind of insult. Which endocrine organs are most susceptible and why? Genetic studies and animal models have revealed some commonalities for these diseases.
openaire +2 more sources
Minerva Endocrinology, 2018
The endocrine system is interested by several autoimmune diseases, characterized by different impact and severity, according to the organs involved. Autoimmune thyroid disorders (i.e. Hashimoto's thyroiditis and Graves' disease) and type 1 diabetes mellitus are the most common autoimmune endocrine disorders, while hypophysitis, adrenalitis (90% of ...
Ruggeri, Rosaria M +2 more
openaire +3 more sources
The endocrine system is interested by several autoimmune diseases, characterized by different impact and severity, according to the organs involved. Autoimmune thyroid disorders (i.e. Hashimoto's thyroiditis and Graves' disease) and type 1 diabetes mellitus are the most common autoimmune endocrine disorders, while hypophysitis, adrenalitis (90% of ...
Ruggeri, Rosaria M +2 more
openaire +3 more sources
Seminars in Nuclear Medicine
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
openaire +2 more sources
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
openaire +2 more sources
Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
openaire +2 more sources
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
openaire +2 more sources