Results 301 to 310 of about 9,455,042 (324)

TP53‐Mutated Myeloid Neoplasms: 2024 Update on Diagnosis, Risk‐Stratification, and Management

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Alterations in the tumor suppressor gene TP53 are common in human cancers and are associated with an aggressive nature. Approximately 8%–12% of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) harbor TP53 mutations (TP53mut) and present immense challenges due to inherent chemoresistance and poor outcomes.
Mithun Vinod Shah   +2 more
wiley   +1 more source

Association of uveitis with pediatric autoimmune diseases based on a TriNetX study. [PDF]

open access: yesSci Rep
Hsu AY   +10 more
europepmc   +1 more source

Corrigendum: Mathematical modeling in autoimmune diseases: from theory to clinical application. [PDF]

open access: yesFront Immunol
Ugolkov Y   +6 more
europepmc   +1 more source

Editorial: Anti-inflammatory diet in autoimmune diseases. [PDF]

open access: yesFront Nutr
Kostoglou-Athanassiou I, Athanassiou P.
europepmc   +1 more source

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua   +11 more
wiley   +1 more source

IL-12 family cytokines and autoimmune diseases: A potential therapeutic target? [PDF]

open access: yesJ Transl Autoimmun
Cui X   +9 more
europepmc   +1 more source

Hereditary Multiple Osteochondromas and Acute Lymphoblastic Leukemia: A Possible Role for EXT1 and EXT2 in Hematopoietic Malignancies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hereditary multiple osteochondromas (HMO) is an autosomal dominant disorder caused by heterozygous deleterious variants in the EXT1 or EXT2 genes. While the clinical core phenotype is well established and mainly consists of bone deformities, limb length discrepancies, multiple benign bone neoplasms, and increased risk of chondrosarcoma, the ...
Francesco Comisi   +7 more
wiley   +1 more source

A Transcriptome‐Wide Mendelian Randomization Study in Isolated Human Immune Cells Highlights Risk Genes Involved in Viral Infections and Potential Drug Repurposing Opportunities for Schizophrenia

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia is a neurodevelopmental psychiatric disorder characterized by symptoms of psychosis, thought disorder, and flattened affect. Immune mechanisms are associated with schizophrenia, though the precise nature of this relationship (causal, correlated, consequential) and the mechanisms involved are not fully understood.
David Stacey   +6 more
wiley   +1 more source

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