Results 311 to 320 of about 704,631 (338)
Medical Clinics of North America, 1965 Evolution has provided chordates an immunological system capable of responding to virtually any antigenic determinant. There is one striking exception to this generality—the immunological system usually fails to respond to antigenic determinants of the host itself.
Noel R. Rose, Keith B. Taylor
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When is an autoimmune disease not an autoimmune disease?
Immunology Today, 1994What are the environmental triggers and genetic susceptibilities underlying the development of autoimmune diseases? These and other questions were addressed at a recent meeting in Finland.
Paavo Toivanen +2 more
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JAMA: The Journal of the American Medical Association, 1982
SYSTEMIC LUPUS ERYTHEMATOSUS Clinical Features Systemic lupus erythematosus (SLE) is a multisystem disorder characterized by the presence of a variety of autoantibodies that are responsible for immunopathologically mediated tissue injury. It is the prototype for a group of disorders that are referred to as the systemic autoimmune or connective tissue
Peter F. Kohler, John H. Vaughan
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SYSTEMIC LUPUS ERYTHEMATOSUS Clinical Features Systemic lupus erythematosus (SLE) is a multisystem disorder characterized by the presence of a variety of autoantibodies that are responsible for immunopathologically mediated tissue injury. It is the prototype for a group of disorders that are referred to as the systemic autoimmune or connective tissue
Peter F. Kohler, John H. Vaughan
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JAMA: The Journal of the American Medical Association, 1987
SINCE the earliest descriptions of the immune system, the ability of an individual to react to a wide variety of foreign and endogenous antigens, while not responding to one's own self, has intrigued researchers. The first descriptions of autoimmune phenomena in the early 1900s aroused sufficient anxiety to cause Ehrlich to coin the term "horror ...
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SINCE the earliest descriptions of the immune system, the ability of an individual to react to a wide variety of foreign and endogenous antigens, while not responding to one's own self, has intrigued researchers. The first descriptions of autoimmune phenomena in the early 1900s aroused sufficient anxiety to cause Ehrlich to coin the term "horror ...
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Autoimmunity and Celiac Disease
Mini-Reviews in Medicinal Chemistry, 2008In celiac disease (CD), abnormal immune-mediated responses follow ingestion of gluten. Although the triggering agent is a dietary protein, the disease has autoimmune components because of the presence of autoantibodies and its association with autoimmune conditions.
GIANFRANI C +2 more
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Scientific American, 1965
Publisher Summary This chapter discusses autoimmune diseases. Immunologic response has specific resistance to infectious diseases. Immunity by our present concept is the basis of the biologic uniqueness and integrity of the individual animal. The hallmark of immunity—as distinguished from inflammation in general—is its specificity.
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Publisher Summary This chapter discusses autoimmune diseases. Immunologic response has specific resistance to infectious diseases. Immunity by our present concept is the basis of the biologic uniqueness and integrity of the individual animal. The hallmark of immunity—as distinguished from inflammation in general—is its specificity.
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The Indian Journal of Pediatrics, 2002
Autoimmune liver disorders are inflammatory liver diseases characterised histologically by a dense mononuclear cell infiltrate in the portal tract and serologically by the presence of non-organ and liver specific autoantibodies and increased levels of immunoglobulin G (IgG), in the absence of a known etiology.
Mieli-Vergani, G, Vergani, D
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Autoimmune liver disorders are inflammatory liver diseases characterised histologically by a dense mononuclear cell infiltrate in the portal tract and serologically by the presence of non-organ and liver specific autoantibodies and increased levels of immunoglobulin G (IgG), in the absence of a known etiology.
Mieli-Vergani, G, Vergani, D
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Infection, autoimmunity and autoimmune disease
1996Studies of the immune response of mammals to infectious agents have revealed that members of the hsp60 and hsp 70 family are highly immunodominant. Given their high conservation during evolution this was surprising, because of the apparent risk of triggering of autoimmunity and autoimmune disease during the defense of a mammal against infection ...
U. Feige, W. van Eden
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Celiac Disease and Autoimmunity
Journal of Pediatric Gastroenterology and Nutrition, 2014ABSTRACTCeliac disease (CD) has a multifactorial etiology with complex genetics and frequently occurs in association with other autoimmune disorders. Even though triggered by a dietary antigen, it shows many autoimmune features, the most peculiar being the presence of high titers of anti‐tissue transglutaminase 2 autoantibodies, produced in the small ...
TRONCONE, RICCARDO, DISCEPOLO, VALENTINA
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Seronegative Autoimmune Diseases
Annals of the New York Academy of Sciences, 2009A close relationship exists between autoimmunity and autoantibodies; despite this, some patients are persistently negative for disease‐specific autoantibodies. These conditions have been defined as seronegative autoimmune diseases. Although the prevalence of seronegative autoimmune diseases is low, they may represent a practical problem because they ...
ALESSANDRI, cristiano +5 more
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