Results 41 to 50 of about 704,631 (338)

MicroRNA in autoimmunity and autoimmune diseases

Journal of Autoimmunity, 2009
MicroRNAs (miRNAs) are small conserved non-coding RNA molecules that post-transcriptionally regulate gene expression by targeting the 3' untranslated region (UTR) of specific messenger RNAs (mRNAs) for degradation or translational repression.
Department of Oral Surgery, Diagnostic Sciences, University of Florida, Gainesville, FL, USA ( host institution ), Pauley, Kaleb M., Cha, Seunghee, Chan, Edward K.L.   +4 more
openaire   +4 more sources

Autoimmune Disease Genetics [PDF]

Clinical and Developmental Immunology, 2012
Genetic risk factors play an important role in autoimmune disease susceptibility. Recent advances genotyping techniques, statistical methods, and the organization of large patient cohorts have facilitated explosive progress in this field, and our understanding of the genetic architecture of human autoimmunity is rapidly expanding.
Mohammed Tikly, Timothy B. Niewold, Shervin Assassi, George N. Goulielmos   +3 more
openaire   +3 more sources

Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough?

Lupus Science and Medicine
Objective To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort.Methods Observational study of routine clinical care data. We selected inception patients treated with
Guillermo Ruiz-Irastorza, Daniel Martín-Iglesias, Ioana Ruiz-Arruza, Fernando Arizpe, Victor Moreno-Torres, Diana Paredes-Ruiz, Valerio Campos-Rodriguez, Laura Amo   +7 more
doaj   +1 more source

A case report of esophageal cancer in a patient with pemphigus vulgaris: A coincidence or something beyond that?

Cancer Reports, 2023
Background Pemphigus is a group of rare but serious autoimmune blistering disorders, affecting skin and mucus membrane. Different reports have been published in respect to the coexistence of pemphigus with neoplasms, especially lympho‐proliferative ones.
Kamran Balighi, Zeinab Aryanian, Shadi Balighi, Ifa Etesami, Parvaneh Hatami   +4 more
doaj   +1 more source

Shared genetic variants suggest common pathways in allergy and autoimmune diseases. [PDF]

, 2016
BACKGROUND: The relationship between allergy and autoimmune disorders is complex and poorly understood. OBJECTIVE: To investigate commonalities in genetic loci and pathways between allergy and autoimmune diseases to elucidate shared disease mechanisms ...
Adnan Custovic, Alan James, Alexessander Couto Alves, Ananieva, Andersson, Angela Simpson, Bach, Barrett, Bergamaschi, Bhatt, Bønnelykke, Carla M.T. Tiesler, Chen, Chevalier, Clark, Cotsapas, Cotsapas, Craig E. Pennell, David Hinds, David P. Strachan, Dirkje S. Postma, Du, Elaine Fuertes, Elangovan, Eskil Kreiner, Farh, Ferreira, Ferreira, Franke, Fujita, Gerard H. Koppelman, Gohlke, Gudbjartsson, Han, Hans Bisgaard, Hinds, Hirota, Jeffery, Joel N. Hirschhorn, Johannes Waage, John Henderson, Jostins, Joyce Y. Tung, Klaus Bønnelykke, Koch, Kofler, Lango Allen, Lee, Li, Lloyd, Lude Franke, Maier, Manuel A. Ferreira, Marie Standl, Marjo-Riitta Jarvelin, Maurano, Mells, Moffatt, Nair, Nicholas Timpson, Nicole M. Warrington, Palmer, Paternoster, Pers, Petukhova, Pittet, Rabin, Rudwaleit, Sawcer, Sevelsted, Sirota, Stahl, Steinman, Susanne Brix, Tak, Takimoto, Terrados, Tune H. Pers, Urayama, Verhoef, Wang, Welter, Yan, Yoshida, Zhernakova   +84 more
core   +4 more sources

Sarcoidosis as an Autoimmune Disease [PDF]

Frontiers in Immunology, 2020
Despite the large number of performed studies, the etiology and pathogenesis of sarcoidosis still remain unknown. Most researchers allude to the possible autoimmune or immune-mediated genesis of the disease. This review attempts an integral analysis of currently available information suggesting an autoimmune genesis of sarcoidosis and is divided into ...
Anna A. Starshinova, Anna M. Malkova, Natalia Y. Basantsova, Natalia Y. Basantsova, Yulia S. Zinchenko, Yulia S. Zinchenko, Igor V. Kudryavtsev, Igor V. Kudryavtsev, Igor V. Kudryavtsev, Gennadiy A. Ershov, Lidia A. Soprun, Vera A. Mayevskaya, Leonid P. Churilov, Leonid P. Churilov, Piotr K. Yablonskiy, Piotr K. Yablonskiy   +15 more
openaire   +4 more sources

Knowledge and Attitude of Iranian University Students toward Genital Warts

Interdisciplinary Perspectives on Infectious Diseases, 2022
Human papillomavirus (HPV) is one of the well-known causes of cervical cancer and one of the most prevalent sexually transmitted diseases (STDs). Since cervical cancer is one of the most common causes of morbidity and mortality in women, this study was ...
Zeinab Aryanian, Maedeh Mohammadi, Arefeh Babazadeh, Parvaneh Hatami, Zeinab Mohseni Afshar, Azadeh Goodarzi, Ifa Etesami, Mohammad Barary, Soheil Ebrahimpour, Parisa Sabbagh   +9 more
doaj   +1 more source

Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis [PDF]

, 2018
Medicinal plants as a rich pool for developing novel small molecule therapeutic medicine have been used for thousands of years. Carnosol as a bioactive diterpene compound originated from Rosmarinus officinalis (Rosemary) and Salvia officinalis, herbs ...
Fei Zhang, Guang-Xian Zhang, Juan-Juan Han, Li Zhao, Lin Zhu, Shuai Liu, Xing Li, Xing Li, Yuan Zhang, Yuan Zhang, Zhe-Zhi Wang   +10 more
core   +3 more sources

A Comparative Study of Demographic and Clinical Criteria Between Male and Female Patients With Pemphigus Referred to a Referral Hospital in Iran

Dermatology Research and Practice
Conclusion: The study highlights significant gender differences in the presentation and severity of pemphigus, underscoring the importance of gender-specific approaches in the diagnosis and management of this condition.
Zeinab Aryanian, Kamran Balighi, Nafiseh Esmaeli, Maryam Daneshpazhooh, Nasim Mazloomi Tootoonchi, Zahra Razavi, Fereshteh Beigmohammadi, Umamah Gul, Azadeh Khayyat, Parvaneh Hatami   +9 more
doaj   +1 more source

Enhanced cytotoxic effect of camptothecin nanosponges in anaplastic thyroid cancer cells in vitro and in vivo on orthotopic xenograft tumors

Drug Delivery, 2017
Anaplastic carcinoma of the thyroid (ATC) is a lethal human malignant cancer with median survival of 6 months. To date, no treatment has substantially changed its course, which makes urgent need for the development of novel drugs or novel formulations ...
Casimiro Luca Gigliotti, Benedetta Ferrara, Sergio Occhipinti, Elena Boggio, Giuseppina Barrera, Stefania Pizzimenti, Mirella Giovarelli, Roberto Fantozzi, Annalisa Chiocchetti, Monica Argenziano, Nausicaa Clemente, Francesco Trotta, Caterina Marchiò, Laura Annaratone, Renzo Boldorini, Umberto Dianzani, Roberta Cavalli, Chiara Dianzani   +17 more
doaj   +1 more source