Results 41 to 50 of about 9,611,247 (349)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han +4 more
doaj +1 more source
Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment
International Journal of Women's Dermatology, 2019 Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study, we tried to clarify the underlying signaling pathways and their roles
Soheil Tavakolpour, PhD +5 more
doaj +1 more source
Treg Enhancing Therapies to Treat Autoimmune Diseases
International Journal of Molecular Sciences, 2020 Regulatory T cells (Tregs) are a small yet critical subset of CD4+ T cells, which have the role of maintaining immune homeostasis by, for example, regulating self-tolerance, tumor immunity, anti-microbial resistance, allergy and transplantation rejection.
P. Eggenhuizen, B. H. Ng, J. Ooi
semanticscholar +1 more source
Vaccinations and Autoimmune Diseases [PDF]
Vaccines, 2021 Vaccines represent one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities. Vaccines are extremely safe, however, no vaccine is completely free from risks and adverse events can occur following vaccination.
Bianca Olivieri +2 more
openaire +3 more sources
Memory CD4+ T Cells in Immunity and Autoimmune Diseases
Cells, 2020 CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is known about the effector function of Th cells in combating pathogens and promoting autoimmune diseases, the roles and biology of memory CD4+ Th cells are complex
Itay Raphael +2 more
semanticscholar +1 more source
Cytokine and autoantibody clusters interaction in systemic lupus erythematosus
Journal of Translational Medicine, 2017 Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco +11 more
doaj +1 more source
Serotonin: A Potent Immune Cell Modulator in Autoimmune Diseases
Frontiers in Immunology, 2020 Serotonin, also known as 5-hydroxytryptamine (5-HT) is a signaling mediator that regulates emotion, behavior, and cognition. Previous studies have focused more on the roles of 5-HT in the central nervous system (CNS).
Minjie Wan +4 more
semanticscholar +1 more source
Clinical Case Reports, 2021 Thrombocytosis is an unusual side effect of all‐trans retinoic acid (ATRA) treatment that occurs in some patients with acute promyelocytic leukemia (APL).
Maryam Habibi +2 more
doaj +1 more source
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases
Arthritis & Rheumatology, 2020 Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes early diagnosis and effective treatment, issues that may be addressed if patients could be classified into groups defined by molecular pattern.
G. Barturen +130 more
semanticscholar +1 more source
Two cases of neglected leishmaniasis with marked facial disfigurement: A diagnostic conundrum
Clinical Case Reports, 2023 Key Clinical Message There is a need to pay more attention to cutaneous leishmaniasis in endemic regions which may mimic other dermatoses and treatment should be initiated with a strong clinical suspicion even without any histopathologic or PCR ...
Zeinab Aryanian +5 more
doaj +1 more source