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Emerging patterns of genetic overlap across autoimmune disorders. [PDF]
Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A+1 more
core +1 more source
Autoimmune Thyroid Disease [PDF]
Abstract Along with neoplasia, autoimmunity is the most common cause of endocrine disease, and of this group of disorders, thyroid autoimmunity is the most frequent. Conversely, the autoimmune thyroid diseases are the most common organ-specific or non-organ-specific autoimmune conditions affecting any site.
openaire +5 more sources
Citrullinated peptides are used for measuring anticitrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA). Accumulation of citrullinated proteins in the inflamed synovium suggests that they may be good targets for inducing peripheral ...
Smadar Gertel+7 more
doaj +1 more source
Autoimunosne bolesti su vrlo heterogena skupina bolesti, koje imaju zajedničku karakteristiku, a to je proizvodnja autoreaktivnih T-stanica ili autoreaktivnih antitijela.
Perić, Maja
core +3 more sources
Autoimmune disease represents a group of more than 60 different chronic autoimmune diseases that affect approximately 6% of the population. Autoimmune diseases arise when ones immune system actively targets and destroys self tissue resulting in clinical ...
core +1 more source
Vaccinations and Autoimmune Diseases [PDF]
Vaccines represent one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities. Vaccines are extremely safe, however, no vaccine is completely free from risks and adverse events can occur following vaccination.
Bianca Olivieri+2 more
openaire +3 more sources
HLA Class I or Class II and Disease Association: Catch the Difference if You Can [PDF]
The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. The recently introduced genome-wide association studies (GWAS) have suggested that several genes
Fiorillo, Mt+3 more
core +2 more sources
Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han+4 more
doaj +1 more source
COVID GEAS: COVID-19 National Survey in Patients With Systemic Autoimmune Diseases
ObjectivesCOVID-19 outcomes in population with systemic autoimmune diseases (SAD) remain poorly understood. The aim was to examine demographic and clinical factors associated with COVID-19 infection in people with rheumatic disease.MethodsTwo phases ...
Borja Del Carmelo Gracia+7 more
doaj +1 more source
Treg Enhancing Therapies to Treat Autoimmune Diseases
Regulatory T cells (Tregs) are a small yet critical subset of CD4+ T cells, which have the role of maintaining immune homeostasis by, for example, regulating self-tolerance, tumor immunity, anti-microbial resistance, allergy and transplantation rejection.
P. Eggenhuizen, B. H. Ng, J. Ooi
semanticscholar +1 more source