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Autoimmune Thyroid Disease [PDF]
Endocrine, 2004 Abstract Along with neoplasia, autoimmunity is the most common cause of endocrine disease, and of this group of disorders, thyroid autoimmunity is the most frequent. Conversely, the autoimmune thyroid diseases are the most common organ-specific or non-organ-specific autoimmune conditions affecting any site.
openaire +5 more sources
Emerging patterns of genetic overlap across autoimmune disorders. [PDF]
, 2012 Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A +1 more
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Treg Enhancing Therapies to Treat Autoimmune Diseases
International Journal of Molecular Sciences, 2020 Regulatory T cells (Tregs) are a small yet critical subset of CD4+ T cells, which have the role of maintaining immune homeostasis by, for example, regulating self-tolerance, tumor immunity, anti-microbial resistance, allergy and transplantation rejection.
P. Eggenhuizen, B. H. Ng, J. Ooi
semanticscholar +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 Based on previous studies, 66 2-phenyl-4H-chromone derivatives containing amide and 1,3,4-oxadiazole moieties were prepared as potential telomerase inhibitors.
Xu Han +4 more
doaj +1 more source
Memory CD4+ T Cells in Immunity and Autoimmune Diseases
Cells, 2020 CD4+ T helper (Th) cells play central roles in immunity in health and disease. While much is known about the effector function of Th cells in combating pathogens and promoting autoimmune diseases, the roles and biology of memory CD4+ Th cells are complex
Itay Raphael +2 more
semanticscholar +1 more source
, 2009 Autoimunosne bolesti su vrlo heterogena skupina bolesti, koje imaju zajedničku karakteristiku, a to je proizvodnja autoreaktivnih T-stanica ili autoreaktivnih antitijela.
Perić, Maja
core +3 more sources
Vaccinations and Autoimmune Diseases [PDF]
Vaccines, 2021 Vaccines represent one of the most effective measures of public health medicine, saving countless lives and preventing lifelong disabilities. Vaccines are extremely safe, however, no vaccine is completely free from risks and adverse events can occur following vaccination.
Bianca Olivieri +2 more
openaire +3 more sources
HLA Class I or Class II and Disease Association: Catch the Difference if You Can [PDF]
, 2017 The association of autoimmune diseases with HLA has been known for many decades. To date, however, the underlying mechanisms have not been fully understood. The recently introduced genome-wide association studies (GWAS) have suggested that several genes
Fiorillo, Mt +3 more
core +2 more sources
Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases
Arthritis & Rheumatology, 2020 Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes early diagnosis and effective treatment, issues that may be addressed if patients could be classified into groups defined by molecular pattern.
G. Barturen +130 more
semanticscholar +1 more source
HLA-B27 Positivity: associated health implications [PDF]
, 2011 HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L. +4 more
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