Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) is limited to an accelerated recovery. We aimed to evaluate the impact of time from symptoms onset to IVMP initiation and of IVMP dose on visual recovery among people with MS‐ON.
Hadar Gilad+3 more
wiley +1 more source
Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4. [PDF]
Autoimmune NZB/NZW mice were treated with weekly injections of monoclonal antibody (mAb) to L3T4, an antigen expressed on a distinct subpopulation of T cells that respond to class II major histocompatibility antigens.
Seaman, WE, Wofsy, D
core +1 more source
HLA-DR2–restricted responses to proteolipid protein 95-116 peptide cause autoimmune encephalitis in transgenic mice [PDF]
Kazuyuki Kawamura+8 more
openalex +1 more source
Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale+14 more
wiley +1 more source
Clinical Signs for Identifying Autoimmune Encephalitis in Psychiatric Patients [PDF]
Autoimmune mechanisms causing diverse psychiatric symptoms are increasingly recognized and brought about a paradigm shift in neuropsychiatry. Identification of underlying antibodies against neuronal ion channels or receptors led to the speculation that a
Herken, Julia, Pruess, Harald
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Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis [PDF]
Tobias Suter+7 more
openalex +1 more source
Cortical ribbon sign: Initial sign of Creutzfeldt–Jakob disease
Journal of General and Family Medicine, EarlyView.
Shiori Nakamichi+4 more
wiley +1 more source
Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher+10 more
wiley +1 more source
'A light in a very dark place' : The role of a voluntary organisation providing support for those affected by encephalitis [PDF]
Voluntary organisations are seen as contributing to the ‘democratisation’ of health and social care. Little, however, is written about their role and this paper, by focusing on the work of The Encephalitis Society, provides insights into the challenges ...
Adamson J.+19 more
core +1 more source
Fulminant Autoimmune Cortical Encephalitis Associated With Thymoma Treated With Plasma Exchange [PDF]
Otis B. Rickman+4 more
openalex +1 more source