Results 161 to 170 of about 51,530 (306)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen   +3 more
wiley   +1 more source

Effect of time to initiation and dose of methylprednisolone on outcome in multiple sclerosis‐related optic neuritis

open access: yesClinical and Experimental Neuroimmunology, EarlyView.
Abstract Objectives It is known that the benefit of intravenous methylprednisolone (IVMP) in multiple sclerosis‐related optic neuritis (MS‐ON) is limited to an accelerated recovery. We aimed to evaluate the impact of time from symptoms onset to IVMP initiation and of IVMP dose on visual recovery among people with MS‐ON.
Hadar Gilad   +3 more
wiley   +1 more source

Can the large language model ChatGPT‐4omni predict outcomes in adult patients with status epilepticus?

open access: yesEpilepsia, Volume 66, Issue 3, Page 674-685, March 2025.
Abstract Objective Large language models (LLMs) have recently gained attention for clinical decision‐making and diagnosis. This study evaluates the performance of the recently updated LLM Chat Generative Pre‐Trained Transformer‐4omni (ChatGPT‐4o) in predicting clinical outcomes in patients with status epilepticus and compares its prognostic performance
Simon A. Amacher   +10 more
wiley   +1 more source

Autoimmune limbic encephalitis and anesthesia [PDF]

open access: bronze, 2013
Chrysanthi Batistaki   +2 more
openalex   +1 more source

Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia‐Romagna region, Italy

open access: yesEpilepsia, Volume 66, Issue 3, Page 753-767, March 2025.
Abstract Objective The STEPPER (Status Epilepticus in Emilia‐Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia‐Romagna region (ERR), Northern Italy.
Lidia Di Vito   +56 more
wiley   +1 more source

Immunity and neuroinflammation in early stages of life and epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The immune system is crucial for the correct brain development, and recent findings also point toward central control of immune response. As the immune system is not fully developed at birth, the early years become an important window for infections and for the development of epilepsy.
Angelica Vega García   +5 more
wiley   +1 more source

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