Results 51 to 60 of about 57,020 (303)

Innate and adaptive immunity in human epilepsies [PDF]

, 2017
Inflammatory mechanisms have been increasingly implicated in the origin of seizures and epilepsy. These mechanisms are involved in the genesis of encephalitides in which seizures are a common complaint.
Bauer, J., Becker, A. (Albert), Beghi, C. (Cesare), Elyaman, W. (Wassim), Peltola, J. (Jukka), Rüegg, S. (Stephan), Titulaer, M.J. (Maarten), Varley, J.A. (James A.)   +7 more
core   +9 more sources

NMDA Autoimmune Encephalitis and Severe Persistent Hypokalemia in a Pregnant Woman

Brain Sciences, 2022
Introduction: For more than a decade, NMDAR autoimmune encephalitis has been studied and treated as a neurological condition, and good results have been achieve through immune therapies.
Daniela Reisz, Iulia-Gabriela Gramescu, Stefan Mihaicuta, Florina Georgeta Popescu, Doina Georgescu   +4 more
doaj   +1 more source

Assessment of long-term psychosocial outcomes in N-methyl-D-aspartate receptor encephalitis – the SAPIENCE study protocol

BMC Neurology
Background N-methyl-D-aspartate-receptor (NMDAR) encephalitis is a rare neurological autoimmune disease with severe neuropsychiatric symptoms during the acute phase.
Ole Jonas Boeken, Josephine Heine, Marta Duda-Sikula, Víctor Patricio, Géraldine Picard, Chloé Buttard, Marie Benaiteau, Álvaro Mendes, Fuchsia Howard, Ava Easton, Donata Kurpas, Jérôme Honnorat, Josep Dalmau, Carsten Finke   +13 more
doaj   +1 more source

Myasthenia gravis complicated with autoimmune encephalitis: a review

Frontiers in Neurology
ObjectiveThis review aims to provide updated information about myasthenia gravis (MG) complicated with autoimmune encephalitis.BackgroundMG and autoimmune encephalitis are both antibody-mediated disorders with a need for active and individually adapted ...
Nils Erik Gilhus, Nils Erik Gilhus
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Therapeutic decision making in autoimmune and inflammatory disorders of the central nervous system in children. [PDF]

, 2016
Autoimmune and inflammatory disorders of the central nervous system can result in significant morbidity and mortality. Through the recognition of syndromes using diagnostic biomarkers, the clinician is now able to use immune suppressive therapies to ...
Dale, Rc, Lim, M., Nosadini, M
core   +3 more sources

Anti-PD1-/PDL1-induced chronic intestinal pseudo-obstruction: three cases treated with vedolizumab after corticosteroid failure with mixed results

Cancer Immunology, Immunotherapy
Immune checkpoint inhibitors (ICI), i.e., anti-PD1/PDL1 and anti-CTLA-4, have reshaped the prognosis of many cancers. Increased use of ICI has led to the onset of new adverse events.
Morgan Zenatri, Michael Collins, Tifanie Alberto, Antonio Farina, Sophie Collardeau-Frachon, Mélanie Saint-Jean, François Bocquet, Frederic Dumont, Jérôme Honnorat, Bastien Joubert, Judith Raimbourg   +10 more
doaj   +1 more source

Autoimmune causes of encephalitis syndrome in Thailand: prospective study of 103 patients [PDF]

, 2013
Background: Data on encephalitis in Thailand have not been completely described. Etiologies remain largely unknown. We prospectively analyzed 103 Thai patients from 27 provinces for the causes of encephalitis using clinical, microbiological and ...
Callahan, Michael, Deesudchit, Tayard, Hemachudha, Thiravat, Mahavihakanont, Aekkapol, Saraya, Abhinbhen, Shuangshoti, Shanop, Sittidetboripat, Nuntaporn, Wacharapluesadee, Supaporn, Wilde, Henry   +8 more
core   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source