Results 61 to 70 of about 57,020 (303)

HLA‐B27 association of autoimmune encephalitis induced by PD‐L1 inhibitor

Annals of Clinical and Translational Neurology, 2020
Objective While immune checkpoint inhibitors are increasingly used for various cancers, unpredictable immune‐related adverse events (irAEs) such as autoimmune encephalitis is life‐threatening.
Hyeyeon Chang, Yong‐Won Shin, Bhumsuk Keam, Miso Kim, Seock‐Ah Im, Soon‐Tae Lee   +5 more
doaj   +1 more source

Deletion of Lymphatic PD-L1 Protects Mice From Severe Autoimmune Encephalitis. [PDF]

Eur J Immunol
Lymphatic endothelial cells at the cribriform plate and in brain‐draining cervical lymph nodes express PD‐L1 during autoimmune encephalitis. Unexpectedly, deletion of lymphatic PD‐L1 expression ameliorates disease symptoms and is associated with increased brain infiltration of regulatory CD8+ Foxp3+ T cells.
Wang Z, Meuffels E, Ashworth C, Reynaud E, Hemanna S, Becher B, Detmar M, Mundt S, Dieterich LC.   +8 more
europepmc   +2 more sources

Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]

, 2018
Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

A case of anti-VGKC antibody encephalitis and prolonged encephalopathy despite spontaneous resolution of imaging abnormalities

Journal of Community Hospital Internal Medicine Perspectives, 2020
Anti-voltage-gated potassium channel (anti-VGKC) antibody encephalitis is a common form of autoimmune encephalitis (AE). AE is usually associated with autoimmune diseases or paraneoplastic phenomena such as seen in small cell lung cancer.
Victoria Novoselova, Vikas Kumar, Niranjan N. Singh, Alexandre Lacasse   +3 more
doaj   +1 more source

'A light in a very dark place' : The role of a voluntary organisation providing support for those affected by encephalitis [PDF]

, 2007
Voluntary organisations are seen as contributing to the ‘democratisation’ of health and social care. Little, however, is written about their role and this paper, by focusing on the work of The Encephalitis Society, provides insights into the challenges ...
Adamson J., Alvesson M., Atkin K., Atkin K., Ava Easton, Barnes C., Boddy M., Bourdieu P., Bury M., Crack S., Dowell E., Habermas J., Hussain-Gambles M., Karl Atkin, Philippa Hare, Ross Barnett J., Ryan M., Silverman D., Williams F., Wistow G.   +19 more
core   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Common EEG Patterns in Autoimmune Encephalitis and Paraneoplastic Neurological Syndromes

Archives of Epilepsy, 2016
Autoimmune encephalitis is a group of syndromes with subacute onset of amnesia, confusion and prominent seizures which may have paraneoplastic or immune-mediated etiology.
Leyla BAYSAL KIRAÇ
doaj   +1 more source

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4. [PDF]

, 1985
Autoimmune NZB/NZW mice were treated with weekly injections of monoclonal antibody (mAb) to L3T4, an antigen expressed on a distinct subpopulation of T cells that respond to class II major histocompatibility antigens.
Seaman, WE, Wofsy, D
core   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source