Results 91 to 100 of about 69,560 (333)

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]

, 2010
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie, Douglas, Kenneth W., Green, Rachel, Pollock, Kevin G.J., Young, David   +4 more
core   +1 more source

Abatacept as salvage therapy for life-threatening refractory autoimmune hemolytic anemia: a case report [PDF]

, 2023
Joerg Hoffmann, Georg Schliesser, Andreas Neubauer   +2 more
openalex   +1 more source

Risk factors for silent cerebral infarction in immune‐mediated thrombotic thrombocytopenic survivors

British Journal of Haematology, EarlyView.
Summary Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) survivors are predisposed to silent cerebral infarctions (SCI) defined as radiological evidence of brain ischaemia without focal symptoms. This study examined risk factors associated with SCI burden in iTTP survivors during remission.
Binish Javed, Jia Yu, Jenna Brown, Jay Meade, Gloria F. Gerber, Michael B. Streiff, Peggy Kraus, Samuel Merrill, Allyson M. Pishko, Jennifer Yui, Rakhi P. Naik, Robert A. Brodsky, Doris D. Lin, Shruti Chaturvedi   +13 more
wiley   +1 more source

Refractory autoimmune hemolytic anemia in a systemic lupus erythematosus patient: A clinical case report

Clinical Case Reports, 2022
Warm autoimmune hemolytic anemia (AIHA) is a hematologic disorder with an incidence of 1–3 per 105 individuals/year. Patients with systemic lupus erythematosus (SLE) develop AIHA in 3% of adult cases and 14% of pediatric cases.
Lake R. Crawford, Natalia Neparidze
doaj   +1 more source

Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report

Journal of Nepal Medical Association, 2023
Autoimmune hemolytic anaemia is a relatively rare disorder caused by autoantibodies directed against self-red blood cells. Though autoimmune thyroid disease is associated with other autoimmune diseases, only a few cases of Hashimoto's thyroiditis with ...
Prakriti Karki, Parikshit Prasai, Vivek Acharya Chetri, Arun Gautam, Robin Maskey   +4 more
doaj   +1 more source

IMpower010: 5‐Year Outcomes of Atezolizumab in Japanese Patients With Resected Stage IB–IIIA Non‐Small Cell Lung Cancer

Cancer Science, EarlyView.
The global Phase 3 IMpower010 study (NCT02486718) evaluated atezolizumab versus best supportive care (BSC) after complete resection and adjuvant platinum‐based chemotherapy in patients with stage IB–IIIA non‐small cell lung cancer (NSCLC). Here, we report updated efficacy and safety results from the disease‐free survival (DFS) final and overall ...
Morihito Okada, Shunichi Sugawara, Yasutaka Watanabe, Haruhiro Saito, Toyofumi F. Chen‐Yoshikawa, Yasushi Goto, Wataru Nishio, Shizuka Nakagawa, Morihiko Hayashi, Hirotsugu Kenmotsu   +9 more
wiley   +1 more source

The Prevalence of Peripheral Erythrophagocytosis in Pediatric Immune-Mediated Hemolytic Anemia

Hematology Reports
Background: Peripheral erythrophagocytosis appears to be a unique sign of acquired immune-mediated hemolytic anemia. It is said to be rare but its prevalence among patients with autoimmune hemolytic anemia has not been studied.
Anselm Chi-wai Lee
doaj   +1 more source

Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]

, 2017
Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan, Jazayeri, Hossein E., Rabiee, Mohammad, Rajab, Asodollah, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +6 more
core   +3 more sources

Efficacy of recombinant erythropoietin in autoimmune hemolytic anemia: a multicenter international study

Haematologica, 2020
Citation: Bruno Fattizzo, Marc Michel, Anna Zaninoni, Juri Giannotta, Stephanie Guillet, Henrik Frederiksen, Josephine M.I. Vos, Francesca R. Mauro, Bernd Jilma, Andrea Patriarca, Francesco Zaja, Anita Hill, Sigbiørn Berentsen, and Wilma Barcellini ...
B. Fattizzo, M. Michel, A. Zaninoni, J. Giannotta, S. Guillet, H. Frederiksen, J. Vos, F. Mauro, B. Jilma, A. Patriarca, F. Zaja, A. Hill, S. Berentsen, W. Barcellini   +13 more
semanticscholar   +1 more source