Results 111 to 120 of about 390,354 (198)

DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy

MedComm, Volume 7, Issue 9, September 2026.
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu, Yuqin Jin, Baochao Li, Jie Deng, Yiwen Zhou, Jinglun Zhang, Huang Li   +6 more
wiley   +1 more source

Autoimmune hemolytic anemia in children

Pediatric Hematology Oncology Journal
Autoimmune hemolytic anaemia (AIHA) is an uncommon cause of antibody-induced hemolytic anemia in children. It is divided into three categories: warm AIHA, cold antibody AIHA and paroxysmal cold hemoglobinuria. The diagnostic work-up typically begins with
Dinesh Chandra, Varun Capoor, Ayoniza Maitri, Rahul Naithani   +3 more
doaj   +1 more source

Mechanistic Insights Into Hepatotoxicity‐Induced Liver Cirrhosis and Anemia: Iron Dysregulation, the Hepcidin–Ferroportin Axis, and Emerging Therapeutic Strategies

Organ Medicine, Volume 3, Issue 3, Page 171-185, September 2026.
Patients with alcohol‐associated liver cirrhosis or acetaminophen (APAP) toxicity frequently develop anemia with iron metabolism disturbances. Dysregulation of hepcidin–ferroportin signaling, along with inflammation, oxidative stress, hypoxia, impaired intestinal iron absorption, malnutrition, and gastrointestinal bleeding, contributes to anemia ...
Debabrata Dash, Raj Kumar Koiri
wiley   +1 more source

Rituximab treatment for relapsed autoimmune hemolytic anemia in Evans syndrome

, 2003
A case is reported of idiopathic relapsed autoimmune hemolytic anemia successfully treated with rituximab. A 43-year-old white male patient with past medical history of Evans syndrome was found to have recurrent autoimmune hemolytic anemia.
Galor, Anat, O'Brien, Timothy
core   +1 more source

The Haematological and Biochemical Responses of Goat Bucks to Range Grazing and Indoor Concentrate‐Based Feeding Systems

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
ABSTRACT Background Range grazing remains the principal feed resource for goats in smallholder production systems, particularly in regions where range grazing and intensive concentrate‐based systems coexist. However, expanding cropland has reduced the availability of grazing lands and shifted production toward concentrate‐based feeding systems ...
Selamu Abraham, Yisehak Kechero, Jane Wamatu   +2 more
wiley   +1 more source

Undetectable Glycosylated Hemoglobin in Autoimmune Hemolytic Anemia

We encountered two cases of autoimmune hemolytic anemia (AIHA) with undetectable glycosylated hemoglobin (HbA1C) level at diagnosis.
Mitani, Noriyuki, Taguchi, Akihiko, Sakuragi, Shizu, Shinohara, kenji, Matsui, Kumiko, Matsuda, Kazuhiro, Tanaka, Yoshinori   +6 more
core  

Giant cell hepatitis and autoimmune hemolytic anemia after chickenpox

, 2010
Autoimmune hemolytic anemia with giant cell hepatitis is a distinct entity in children. It is usually fatal with progressive liver disease. Immunosuppressive treatment with conventional drugs offers some response; however, it is usually only temporary ...
Funda OZGENC, Ozgenc, Funda, Kaan KAVAKLI, Sait SEN, Masallah BARAN, Rasit Vural YAGCI, Kavakli, Kaan, Funda YILMAZ, Yagci, Rasit Vural, Baran, Masallah, Omer BERK, Gokce, Demir, Berk, Omer, Yilmaz, Funda, Sen, Sait, Demir GOKCE   +15 more
core   +1 more source

Case report: Identification of a Chinese patient with RAG1 mutations initially presenting as autoimmune hemolytic anemia

Frontiers in Immunology
Mutations in the recombination-activating gene 1, a pivotal component essential for V(D)J recombination and the formation of T- and B-cell receptors, can result in autoimmune hemolytic anemia, a rare hematological condition characterized by the ...
Xin Chen, Chunxue Jiang, Wenliang Song, Tingting Sun, Jingli Yan, Wei Xu, Kai You   +6 more
doaj   +1 more source

Comparative Safety Analysis of Targeted Synthetic and Biologic Disease‐Modifying Antirheumatic Drugs Among Patients With Rheumatoid Arthritis: A Nationwide Cohort Study in Japan

International Journal of Rheumatic Diseases, Volume 29, Issue 9, September 2026.
ABSTRACT Aim To compare risks of malignancy, opportunistic infections, and venous thromboembolism between the targeted synthetic disease‐modifying antirheumatic drugs (tsDMARDs) and biologic DMARDs (bDMARDs) at the 2nd and 3rd lines of therapy (LOT). Methods We conducted a cohort study using the National Database of Health Insurance Claims (2013–2021).
Shiori Nishimura, Toshitaka Hirano, Soko Setoguchi, Hiroki Matsui, Yoshinori Takeuchi, Yasushi Inoue, Yoshiya Tanaka, Kunihiro Yamaoka, Yoichi Ii, Shintaro Hiro, Masato Hoshi, Naonobu Sugiyama, Yutaka Matsuyama, Hiraku Kumamaru   +13 more
wiley   +1 more source

Autoimmune hemolytic anemia

, 1994
Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black
Izui, Shozo
core