Results 41 to 50 of about 33,029 (292)

Severe refractory autoimmune hemolytic anemia with both warm and cold autoantibodies that responded completely to a single cycle of rituximab: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Mixed warm and cold autoimmune hemolytic anemia runs a chronic course with severe intermittent exacerbations. Therapeutic options for the treatment of hemolysis associated with autoimmune hemolytic anemia are limited.
Forte Frank   +6 more
doaj   +1 more source

Success of anti-CD20 monoclonal antibody treatment for severe autoimmune hemolytic anemia caused by warm-reactive immunoglobulin A, immunoglobulin G, and immunoglobulin M autoantibodies in a child: a case report

open access: yesJournal of Medical Case Reports, 2017
Background Autoimmune hemolytic anemia is rare in children. First-line therapies for this disease consist of corticosteroids and intravenously administered immunoglobulin that are effective in most patients. However, a small proportion of cases (5 to 10%)
Houda Ajmi   +8 more
doaj   +1 more source

Isohemagglutinins of Graft Origin after ABO-Unmatched Liver Transplantation [PDF]

open access: yes, 1984
THE increasing success of liver transplantation in recent years has provided an experimental model to study and document the hepatic synthesis of many plasma proteins.12345 The normal hepatobiliary tract has not been regarded as a major source of ...
Anderson   +13 more
core   +1 more source

Autoimmune hemolytic anemia

open access: yesCurrent Opinion in Immunology, 1994
Autoimmune hemolytic anemia (AHA) is characterized by the production of Coombs' antibodies, which are responsible for the destruction of red blood cells (RBCs). Analysis of both monoclonal anti-RBC autoantibodies derived from autoimmune New Zealand black mice and transgenic mice expressing a pathogenic IgM anti-RBC autoantibody has considerably ...
openaire   +4 more sources

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

open access: yes, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
BrĂ©m, Elizabeth   +2 more
core  

Regulatory T Cells Are Dispensable for Tolerance to RBC Antigens [PDF]

open access: yes, 2016
Autoimmune hemolytic anemia (AIHA) occurs when pathogenic autoantibodies against red blood cell (RBC) antigens are generated. Whilst the basic disease pathology of AIHA is well studied, the underlying mechanism(s) behind the failure in tolerance to RBC ...
Amanda L. Richards   +4 more
core   +5 more sources

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

open access: yes, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima   +18 more
core  

Positive predictive value of diagnosis coding for hemolytic anemias in the Danish National Patient Register [PDF]

open access: yes, 2016
PURPOSE: The nationwide public health registers in Denmark provide a unique opportunity for evaluation of disease-associated morbidity if the positive predictive values (PPVs) of the primary diagnosis are known.
Frederiksen, Henrik   +3 more
core   +2 more sources

Treatment of autoimmune hemolytic anemias

open access: yesHaematologica, 2014
Autoimmune hemolytic anemia (AIHA) is a relatively uncommon disorder caused by autoantibodies directed against self red blood cells. It can be idiopathic or secondary, and classified as warm, cold (cold hemagglutinin disease (CAD) and paroxysmal cold hemoglobinuria) or mixed, according to the thermal range of the autoantibody.
Alberto Zanella, Wilma Barcellini
openaire   +4 more sources

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

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