Results 21 to 30 of about 173,185 (344)

Trends in Characteristics, Mortality, and Other Outcomes of Patients With Newly Diagnosed Cirrhosis [PDF]

open access: yes, 2019
Importance: Changes in the characteristics of patients with cirrhosis are likely to affect future outcomes and are important to understand in planning for the care of this population.
Chalasani, Naga   +6 more
core   +1 more source

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

open access: yes, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou   +31 more
core   +1 more source

Occurrence of autoimmune chronic hepatitis in siblings [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. Autoimmune hepatitis is a chronic inflammatory disease of the liver of unknown etiology, characterized by the loss of tolerance against hepatic tissue, leading to the destruction of hepatic parenchyma.
Nožić Darko   +2 more
doaj   +1 more source

Diagnosis of Autoimmune Hepatitis Using International Autoimmune Hepatitis Group Scoring [PDF]

open access: yes, 2013
Autoimmune hepatitis (AIH) is described as T lymphocyte suppressor disturbance, thus there is formation of autoantibody which attacks surface antigen of liver cells or hepatocytes.
Ahmad, H. (Harijono)   +1 more
core   +1 more source

Estimation of Thyroid Gland and Pancreatic Functioning in Patients with Chronic Hepatitis B and C Combined with Autoimmune Thyroiditis and without it

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2012
Chronic viral hepatitis is one of the most urgent problems of the healthcare. Viral hepatitis is not restricted with liver damage; they are like systemic disease proceeding with obligate development of extrahepatic manifestations.
Kh.T. Rustamova   +2 more
doaj   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

open access: yes, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E   +4 more
core   +1 more source

Comorbidities in aging patients with sickle cell disease. [PDF]

open access: yes, 2018
Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core   +2 more sources

Autoimmune Hepatitis

open access: yesArchives of Pediatric Gastroenterology, Hepatology, and Nutrition, 2022
Autoimmune hepatitis (AIH) is a condition caused by self-perpetuating immune response towards hepatocytes in liver. In children, AIH may progressed more rapidly compared to adults.
Fatima Safira Alatas   +3 more
doaj   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

open access: yesHepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah   +2 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

open access: yesHepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai   +29 more
wiley   +1 more source

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