Results 91 to 100 of about 397,447 (350)

Real‐world efficacy and toxicity of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma according to IMDC risk criteria—A multi‐center retrospective analysis on behalf of the GUARDIANS group

International Journal of Cancer, EarlyView.
What's New? The combination of ipilimumab and nivolumab as a first‐line treatment for advanced renal cell carcinoma has demonstrated durable response and tolerability in clinical trials. However, inclusion criteria for clinical studies are restrictive, and patients in the real‐world setting tend to have more comorbidities.
Hendrik Dinkel, Linus Materna, Ramona Stelmach, Stefanie Zschäbitz, Stephanie Neuberger, Can D. Aydogdu, Jozefina Casuscelli, Timo Egenolf, Matteo Silberg, Julie Steinestel, Arne Strauss, Florian Kirchhoff, Marit Ahrens, Pia Paffenholz, Richard Cathomas, Berna C. Özdemir, Christopher Gossler, Philipp Ivanyi, Marc Rehlinghaus, Thomas Hilser, Viktor Grünwald, Katrin Schlack   +21 more
wiley   +1 more source

Thyroid Dysfunction in Primary Biliary Cholangitis: A Comparative Study at Two European Centers [PDF]

, 2017
open10siOBJECTIVES: Primary biliary cholangitis (PBC) is often associated with other autoimmune diseases, but little is known about the influence of thyroid disease (TD) on the natural history of PBC.

core   +1 more source

Anti-inflammatory effects of luteolin on experimental autoimmune thyroiditis in mice.

Experimental and Therapeutic Medicine, 2016
Hashimoto's thyroiditis (HT) is the most common organ-specific autoimmune disease and is believed to be a predominately T cell-mediated autoimmunity. Signal transducer and activator of transcription (STAT)3 is a crucial transcription factor of T cell ...
Nan Xia, Gang Chen, Min Liu, X. Ye, Yahui Pan, Jiuyu Ge, Yan-ting Mao, Hongwei Wang, Jian Wang, Sijing Xie   +9 more
semanticscholar   +1 more source

Presumed Isotretinoin-Induced, Concomitant Autoimmune Thyroid Disease and Ocular Myasthenia Gravis: A Case Report

Case Reports in Dermatology, 2012
Introduction: There are many adverse effects that have been described for isotretinoin. To the best of our knowledge, this is the first report of a possible association of oral isotretinoin intake with autoimmune thyroiditis and ocular myasthenia gravis (
Huseyin Gursoy, Idil Cakmak, Nilgun Yildirim, Hikmet Basmak   +3 more
doaj   +1 more source

Autoantibody signatures in children with celiac disease, juvenile idiopathic arthritis, and polyautoimmunity

JPGN Reports, EarlyView.
Abstract Objective To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 ...
Nan Du, Denis Chang, Madison Wong, Jay R. Thiagarajah, Erin Janssen, Lauren A. Henderson, Krishnan Raghunathan, Jocelyn A. Silvester   +7 more
wiley   +1 more source

Impact of Combined Additional Resections on the Surgical Outcomes of Robot‐Assisted Resection of Thymic Epithelial Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Robot‐assisted thoracoscopy (RATS) is rapidly emerging as the preferred approach for the resection of thymic epithelial tumors (TET). Current challenges include the role of RATS in locally advanced disease and combined additional resections.
Benedikt Niedermaier, Nabil Khan, Florian Eichhorn, Maria Zehentmeier, Heidrun Grosch, Raffaella Griffo, Alessio Campisi, Antonia Margineanu, Michael Allgäuer, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin E. Eichhorn   +12 more
wiley   +1 more source

Understanding the Challenges of Hashimoto's Thyroiditis: Perspectives on Diagnosis, Treatment, and Associated Conditions

Journal of Education, Health and Sport
Introduction: Hashimoto's thyroiditis is a prevalent autoimmune disease among the population. With the progress in diagnostic and research techniques, it has come to light that Hashimoto's thyroiditis is linked to a higher likelihood of developing other
Klaudia Brygida Kułak, Karolina Palacz, Katarzyna Gadżała, Izabela Janik, Marzena Pliszka, Katarzyna Chamera-Cyrek, Anna Maria Koman   +6 more
doaj   +1 more source

Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) presenting as major depression

BMC Psychiatry, 2016
BackgroundHashimoto’s encephalopathy is a neuropsychiatric disease with symptoms of cognitive impairment, stroke-like episodes, seizures, and psychotic or affective symptoms associated with autoimmune thyroiditis and excellent steroid responsiveness ...
D. Endres, E. Perlov, O. Stich, L. Tebartz van Elst   +3 more
semanticscholar   +1 more source

Efficacy of Ritlecitinib for Vitiligo Treatment Stratified by Baseline Demographic and Clinical Characteristics: Post Hoc Analysis of a Phase 2b Study

JEADV Clinical Practice, EarlyView.
This post hoc analysis examined the efficacy of ritlecitinib in subgroups of patients with vitiligo, defined by demographic and clinical characteristics. Patients completed the dose‐ranging and extension periods of the phase 2b study (NCT03715829) of ritlecitinib.
A. G. Pandya, I. Hamzavi, P. Ghosh, K. Ezzedine, J. E. Harris, R. Adiri, S. Chen, E. Peeva, Y. Yamaguchi   +8 more
wiley   +1 more source

Rotavirus vaccination is not associated with incident celiac disease or autoimmune thyroid disease in a national cohort of privately insured children

Scientific Reports, 2022
Rotavirus infection is a potential trigger for autoimmune diseases, and previous reports note associations between rotavirus vaccination and type 1 diabetes. In this report, we examine the association between rotavirus vaccination and autoimmune diseases
Catherine Kim, Zhe Yin, Neil Kamdar, Grace J. Lee   +3 more
doaj   +1 more source