Results 181 to 190 of about 393,919 (333)

The discovery of thyroid autoimmunity

open access: yesImmunology Today, 1991
In 1951 there were not many places where a newly minted PhD could go to learn immunology. Michael Heidelberger was at Columbia working on the immunochemistry of polysaccharides and Ernest Witebsky in Buffalo was engaged mostly in studying human blood groups and isolating the blood group substances.
openaire   +2 more sources

E3 Ubiquitin Ligases: Structures, Biological Functions, Diseases, and Therapy

open access: yesMedComm, Volume 6, Issue 12, December 2025.
E3 ligases function as critical regulators of cellular protein degradation, and their dysregulation is a core pathogenic mechanism in a wide array of human diseases, including cancer, cardiovascular conditions, neurodegenerative disorders, and autoimmune diseases.
Haochen Wang   +6 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, Volume 1, Issue 3, Page 322-358, December 2025.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Acquired Partial Lipodystrophy with Autoimmune Thyroiditis [PDF]

open access: diamond, 2018
Ahu Yorulmaz, Esra Arı, Başak Yalçın
openalex   +1 more source

European Society for the Study of Coeliac Disease 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 1: Diagnostic Approach

open access: yesUnited European Gastroenterology Journal, Volume 13, Issue 10, Page 1855-1886, December 2025.
Infographic. This infographic summarizes the diagnostic approach to CeD in adults, including initial serological testing, histological confirmation, criteria for a no‐biopsy diagnosis, seronegative CeD, potential CeD, and the role of gluten challenge. Source: Authors' own creation (based on current clinical guidelines).
Abdulbaqi Al‐Toma   +20 more
wiley   +1 more source

Isolated Adrenocorticotropic Hormone (ACTH) Deficiency and Thyroid-Stimulating Hormone (TSH)-Thyroid Hormone Derangement: Report of Three Cases [PDF]

open access: yes, 2004
 We present three cases of isolated adrenocorticotropin (ACTH) deficiency accompanied by derangement of the thyroid-stimulating hormone (TSH)-thyroidal axis. Thyroid hormone and TSH levels were evaluated before and after cortisol replacement.
北濱 眞司   +6 more
core  

Incidence of Autoimmune Diseases in 30,340 Danish Women With Polycystic Ovary Syndrome (PCOS) Compared to 151,520 Controls. A National Cohort Study

open access: yesClinical Endocrinology, Volume 103, Issue 6, Page 863-872, December 2025.
ABSTRACT Objective Autoimmunity can be part of the pathogenesis of polycystic ovary syndrome (PCOS), but prospective studies on autoimmune disease in population based cohorts are lacking. This study aimed to investigate incidence rates of autoimmune disease in Danish women with PCOS before and after PCOS diagnosis compared to controls.
Dorte Glintborg   +4 more
wiley   +1 more source

The role of histohematologic barriers and the possibility of using polarization biomedical optics methods in the diagnosis of autoimmune thyroiditis

open access: yesMìžnarodnij Endokrinologìčnij Žurnal
Background. Violation of the integrity of the histohematologic barriers (blood-brain, blood-testis, blood-ocular, blood-labyrinth, blood-thyroid) leads to autoimmune damage to these organs.
Yu.Ye. Rohovyi   +4 more
doaj   +1 more source

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