Background. The leading factor of hypothyroidism in patients with autoimmune thyroiditis is destruction of the thyroid gland under the influence of the autoimmune process.
O.A. Goncharova
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Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]
Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Aliesky, Holly A +4 more
core +7 more sources
Association Kikuchi disease with Hashimoto thyroiditis: a case report and literature review [PDF]
Kikuchi-Fujimoto disease (KFD) is a benign and self-limited disease characterized by fever and lymphadenopathy. The etiology of KFD is unknown, but an autoimmune cause has been suggested.
Eun Joo Lee +3 more
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Background. The review analyzes the publications on the pathogenetic mechanisms and clinical consequences of the impact of autoimmune thyroiditis and hypothyroidism on body systems.
O.V. Shidlovskyy +6 more
doaj +1 more source
Antigenic structure remains a major focus in thyroid immunology. The genes for three major thyroid antigens--thyroglobulin, thyroid peroxidase and the thyrotropin receptor--were sequenced in the late 1980's, and epitopes for antibody and T cells have been reported within the last year.
B R, Champion, A, Cooke, D C, Rayner
openaire +4 more sources
Subacute thyroiditis and rapidly developing goiter in a 16-year-old female: a case report
Subacute thyroiditis (SAT) is an inflammatory disease of the thyroid gland with multiple etiologies and clinical features, often challenging to recognize. The classic presentation is the painful, granulomatous thyroiditis (DeQuervain’s) characterized by
Marcos Estrada +4 more
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Autoimmune Thyroid Disorders [PDF]
Thyroid autoimmunity, as reflected by the presence in serum of autoantibodies directed against the thyroid autoantigens thyroglobulin (Tg) and thyroid peroxidase (TPO), is present in >10% of the US population over 12 years of age [1] and is the most common cause of endocrine dysfunction in iodine-sufficient populations [2].
Brown, Rosalind, Francis, Gary L.
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Autoimmune Hemolytic Anemia with Autoimmune Hypothyroidism: A Case Report
Autoimmune hemolytic anaemia is a relatively rare disorder caused by autoantibodies directed against self-red blood cells. Though autoimmune thyroid disease is associated with other autoimmune diseases, only a few cases of Hashimoto's thyroiditis with ...
Prakriti Karki +4 more
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Thyroid ultrasonography reporting: consensus of Italian Thyroid Association (AIT), Italian Society of Endocrinology (SIE), Italian Society of Ultrasonography in Medicine and Biology (SIUMB) and Ultrasound Chapter of Italian Society of Medical Radiology (SIRM) [PDF]
Thyroid ultrasonography (US) is the gold standard for thyroid imaging and its widespread use is due to an optimal spatial resolution for superficial anatomic structures, a low cost and the lack of health risks.
Cantisani, V. +11 more
core +1 more source
Oxidative stress as a key feature of autoimmune thyroiditis: an update.
INTRODUCTION Oxidative stress has been proposed as one of the factors concurring in the pathophysiology of autoimmune thyroid diseases. Reactive oxygen species are the main expression of oxidative stress in biological systems, and their production can ...
R. Ruggeri +8 more
semanticscholar +1 more source

