Results 141 to 150 of about 436,604 (311)
Cell Transplantation, 2018 As a featured ocular inflammatory disease, autoimmune uveitis is the major cause of blindness in the clinic. Although current immunosuppressive regimens can alleviate the progression of autoimmune uveitis, they have serious side effects.
Jinying Li +12 more
doaj +1 more source
Review of Systemic Immunosuppression for Autoimmune Uveitis [PDF]
, 2014 The purpose of this review is to comprehensively examine the various therapeutic agents available to treat autoimmune eye disease, their indications, clinical safety and recent developments.
Castiblanco, Claudia, Foster, C. Stephen
core +1 more source
ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Mikako Harata, Anne Abel, Ying Jin
wiley +1 more source
Osteopontin Is Proinflammatory in Experimental Autoimmune Uveitis
Investigative Ophthalmology & Visual Science, 2006 Osteopontin (OPN) has been implicated in inflammatory and wound-healing processes. Increased OPN mRNA levels have been reported in experimental autoimmune uveitis (EAU), but the function of OPN in the inflamed eye is unknown. The purpose of this study was to investigate the role of OPN in the pathogenesis of EAU.EAU was induced in OPN-null and wild ...
Sherry T, Hikita +8 more
openaire +2 more sources
The anti-IRBP IgG1 and IgG2a response does not correlate with susceptibility to experimental autoimmune uveitis [PDF]
, 2006 Luciana Vieira de Moraes +5 more
openalex +1 more source
Correction: Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach [PDF]
, 2023 Deborah Lipski +6 more
openalex +1 more source
Azathioprine in the Management of Autoimmune Uveitis
Ocular Immunology and Inflammation, 2008 To evaluate the role of azathioprine as an immunosuppressive for steroid-resistant autoimmune uveitis (AIU).Patients using oral prednisolone for active AIU without clinical response were recruited. A standard protocol of oral prednisolone and azathioprine was used.Twenty-seven patients participated in the study: 3 with anterior uveitis, 1 pars planitis,
Pacheco, Patricio A. +3 more
openaire +3 more sources
Local Delivery of CTLA-4 Blockade Inhibits Growth of Pancreatic Tumors [PDF]
, 2016 Immune checkpoint blockade has demonstrated great potential in activating antitumor immunity. Ipilimumab is a monoclonal antibody which targets cytotoxic T-lymphocyte antigen-4. CTLA-4 belongs to the CD28 class of receptors and is found on the surface of
Baltz, Jack
core +2 more sources
Macrophages and Uveitis in Experimental Animal Models
Mediators of Inflammation, 2015 Resident and infiltrated macrophages play relevant roles in uveitis as effectors of innate immunity and inductors of acquired immunity. They are major effectors of tissue damage in uveitis and are also considered to be potent antigen-presenting cells. In
Salvador Mérida +3 more
doaj +1 more source
In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation. [PDF]
, 2005 Regulatory T cells (Tregs) have been shown to be critical in the balance between autoimmunity and tolerance and have been implicated in several human autoimmune diseases.
Bluestone, JA +6 more
core +1 more source