Results 171 to 180 of about 28,173 (225)

Dietary caloric restriction protects experimental autoimmune uveitis by regulating Teff/Treg balance. [PDF]

iScience
Li Z, Duan R, Jiang Q, Liu J, Chen J, Jiang L, Wang T, Li H, Zhang Y, Peng X, Huang Z, Zhu L, Zou W, Lin Y, Su W.   +14 more
europepmc   +1 more source

Itaconate Ameliorates Experimental Autoimmune Uveitis by Modulating Teff/Treg Cell Imbalance Via the DNAJA1/CDC45 Axis. [PDF]

Invest Ophthalmol Vis Sci
Jiang Q, Li Z, Huang Y, Huang Z, Chen J, Liu X, Zhang C, Gu C, Wang T, Li H, Li Y, Su W.   +11 more
europepmc   +1 more source

Hyaluronic acid-curcumin nanoparticles for preventing the progression of experimental autoimmune uveitis through the Keap1/Nrf2/HO-1 signaling pathway. [PDF]

J Nanobiotechnology
Tang W, Huang X, Yi YD, Cao F, Deng M, Fan J, Jiang ZX, Tao LM, Wang X, Shi L.   +9 more
europepmc   +1 more source

High salt diet alleviates disease severity in native experimental autoimmune uveitis. [PDF]

Front Ophthalmol (Lausanne)
Derluyn N, Foucart V, Verce M, Abdo R, Vaudoisey L, Lipski D, Flamand V, Everard A, Bruyns C, Willermain F.   +9 more
europepmc   +1 more source

Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype. [PDF]

Proc Natl Acad Sci U S A
Li W, He S, Tan J, Li N, Zhao C, Wang X, Zhang Z, Liu J, Huang J, Li X, Zhou Q, Hu K, Yang P, Hou S.   +13 more
europepmc   +1 more source

Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis. [PDF]

Sci Rep
Quinn J, Salman A, Paluch C, Jackson-Wood M, McClements ME, Luo J, Davis SJ, Cornall RJ, MacLaren RE, Dendrou CA, Xue K.   +10 more
europepmc   +1 more source

Immunoregulatory Properties of Immune Cells that Associate with the Lens Capsule Surface during Acute and Resolution Phases of Experimental Autoimmune Uveitis. [PDF]

Am J Pathol
Le PM, Mattapallil MJ, Caspi RR, Stepp MA, Menko AS.   +4 more
europepmc   +1 more source

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Targeting interleukin-6 in autoimmune uveitis

Autoimmunity Reviews, 2017
Interleukin-6 (IL-6) is a key cytokine that is strongly up-regulated during infection and inflammation. Featuring pleiotropic activity, IL-6 is responsible for the induction of hepatic acute-phase proteins, trafficking of acute and chronic inflammatory cells, differentiation of adaptive T cell responses, homeostatic regulation, and tissue regeneration.
Marina, Mesquida, Blanca, Molins, Víctor, Llorenç, Maite Sáinz, de la Maza, Alfredo, Adán   +4 more
openaire   +4 more sources

Tregs in Autoimmune Uveitis

2021
Uveitis is a chronic disease with relapsing and remitting ocular attack, which requires corticosteroids and systemic immunosuppression to prevent severe vision loss. Classically, uveitis is referred to an autoimmune disease, mediated by pro-inflammatory Th17 cells and immunosuppressive CD4+CD25+FoxP3+ T-regulatory cells (Tregs).
Zhaohao, Huang, Wenli, Li, Wenru, Su
openaire   +2 more sources