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TregLymphocytes in Autoimmune Uveitis
Ocular Immunology and Inflammation, 2012To evaluate circulating CD4(+)CD25(+) regulatory T-cell populations in patients with autoimmune uveitis and to assess whether T-regulatory cell populations correlate with clinical features.Sixty-four patients with noninfectious uveitis were enrolled.
Ruggieri S +3 more
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Diagnosis and classification of autoimmune uveitis
Autoimmunity Reviews, 2014Uveitis is the most common ophthalmological finding in the practice of rheumatology and clinical immunology. The condition is frequently idiopathic and defined by the inflammatory status of the uvea, the part of the middle eye that includes the iris, ciliary body and choroid. Anterior uveitis involves the iris and ciliary body, while the posterior form
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Autoimmune uveitis: clinical, pathogenetic, and therapeutic features
Clinical and Experimental Medicine, 2015Autoimmune uveitis (AU), an inflammatory non-infectious process of the vascular layer of the eye, can lead to visual impairment and, in the absence of a timely diagnosis and suitable therapy, can even result in total blindness. The majority of AU cases are idiopathic, whereas fewer than 20 % are associated with systemic diseases.
Prete, Marcella +3 more
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T-lymphocyte subsets in experimental autoimmune uveitis
Clinical Immunology and Immunopathology, 1985The dynamic changes of the lymphocyte subsets in the inflamed ocular tissue in Lewis rats with experimental autoimmune uveitis (EAU) were studied by immunohistopathological evaluation at varying intervals after initiation of the disease. Monoclonal antibodies to specific markers of the rat T-helper/inducer lymphocyte (W3/25) and T-suppressor/cytotoxic ...
C C, Chan +6 more
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Animal Models of Autoimmune Uveitis
2015There are several animal models that have proved useful in understanding the mechanisms and pathogenesis of uveitis. One of the oldest animal models of uveitis widely used is experimental autoimmune uveitis (EAU, Agarwal and Caspi). It can be induced by either injection of specific photoreceptor proteins, such as arrestin (S-antigen) or ...
Jennifer L. Kielczewski, Rachel R. Caspi
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Immune Therapy for Autoimmune Uveitis
1992Intraocular inflammatory disease (uveitis) presents an ongoing challenge to ophthalmologists dealing with this problem. The term “uveitis” has been used since the last century, since it was felt that the problem stemmed from an inflammation of uvea. Today, it is clear that this limited definition is not the case, and the term denotes any intraocular ...
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[Autoimmune etiology of endogenous uveitis].
Ceskoslovenska oftalmologie, 1992The authors presents a review of some findings on the basis of which it is possible to classify uveitis, retinitis and choroiditis already at the time of its onset, and in particular subsequently, as an autoimmune disease. They consider this review an adequate basis for immunosuppression therapy of uveitis at the very onset, although they do not ...
T, Poch, E, Ríhová
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Experimental Models in Autoimmune Uveitis
Autoimmune uveitis, a complex ocular inflammatory disorder, remains a significant challenge in ophthalmology and immunology research. This chapter delves into the intricate world of experimental models designed to mimic autoimmune uveitis in humans.Ahmed M. Al-Hakam +1 more
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