Results 181 to 190 of about 28,173 (225)

Uveitis: Autoimmunity… and beyond

Autoimmunity Reviews, 2019
Uveitis is the most common ophthalmological finding in the practice of rheumatology and clinical immunology. The condition is frequently idiopathic but about 60 causes of uveitis have been described. Our aim was to analyze the clinical patterns and etiologies of uveitis in a tertiary referral center.The records of 912 consecutive patients referred to ...
Pierre-Jean, Bertrand, Yvan, Jamilloux, René, Ecochard, Gaelle, Richard-Colmant, Mathieu, Gerfaud-Valentin, Martin, Guillaud, Philippe, Denis, Laurent, Kodjikian, Pascal, Sève   +8 more
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Treatment of Autoimmune Uveitis

Annals of the New York Academy of Sciences, 1993
The number of effective drugs for the treatment of autoimmune uveitis has greatly increased over the past 40 years. Many patients previously condemned to blindness can now be successfully treated with new immunosuppressive agents. New targets of the immune system, such as cell adhesion molecules, may offer novel therapeutic approaches for the treatment
S M, Whitcup, R B, Nussenblatt
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Uveitis with autoimmune hepatic disorders

Ocular Immunology and Inflammation, 2001
Many cases of uveitis are thought to be autoimmune in nature. We report two cases of panuveitis, one of which was associated with chronic active hepatitis and the other with primary biliary cirrhosis. This suggests that the autoimmune disturbance may have been responsible for the development of the intraocular inflammation.
A, Kamal, A, Bhan, P I, Murray
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Mouse Models of Autoimmune Uveitis

Current Pharmaceutical Design, 2015
Uveitis is a sight threatening intraocular inflammation accounting for approximately 10% of blindness worldwide. On the basis of aetiology, disease can be classified as infectious or non-infectious; and by anatomical localization of inflammation as anterior, posterior and panuveitis.
Izabela P, Klaska, John V, Forrester
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Cutting-Edge Issues in Autoimmune Uveitis

Clinical Reviews in Allergy & Immunology, 2011
Autoimmune uveitis (AIU) is among the leading causes of preventable blindness. It can be isolated, precede, or appear in the course of a systemic autoimmune inflammatory disease. When suspected, AIU should be promptly referred to an ophthalmologist for proper anatomic classification and local treatment.
Roger A, Levy, Francisco Assis, de Andrade, Ivan, Foeldvari   +2 more
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Biologic agents in experimental autoimmune uveitis

International Ophthalmology, 2013
Experimental uveitis models were developed in an effort to elucidate the pathogenesis of human uveitis. The therapeutic effects of numerous anti-inflammatory agents including corticosteroids and immunomodulatory agents including biologic response modifiers have been investigated in both experimental and human uveitis.
Gian Paolo, Giuliari, Ama, Sadaka, David M, Hinkle   +2 more
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Uveitis in Patients with Autoimmune Hepatitis

American Journal of Ophthalmology, 2009
To report seven cases of uveitis occurring in patients with autoimmune hepatitis (AIH), raising the possibility that uveitis may be an extrahepatic feature of AIH.Multicenter, retrospective, observational case series of patients with AIH and uveitis.One index case was identified at Oregon Health & Science University.
Lyndell L, Lim, John D, Scarborough, Jennifer E, Thorne, Elizabeth, Graham, John H, Kempen, Friederike, Mackensen, Quan Dong, Nguyen, Tisha, Prabriputaloong, Russell W, Read, Eric B, Suhler, Jonathan M, Schwartz, Justine R, Smith   +11 more
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Uveitis Complicating Autoimmune Chronic Active Hepatitis

Archives of Pediatrics & Adolescent Medicine, 1983
A patient with autoimmune hepatitis B surface antigen-negative chronic active hepatitis (CAH) developed uveitis during the course of her disease. The occurrence of this eye disorder provides additional support for an autoimmune pathogenesis for CAH.
J N, Bloom, I M, Rabinowicz, S T, Shulman   +2 more
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Uveitis and Autoimmune Diseases

2019
The uvea is the predilection site of ocular immune diseases, due to its features like peripheral immune organ, with abundant vessels and some other ocular antigenic substances such as lens and retinal antigens, which could easily induce the immune-related ocular diseases. Uveitis has many complex symptoms, signs, and causes.
Meifen Zhang, Bo Wan
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Mechanisms Underlying Autoimmune Uveitis

Drug Discovery Today: Disease Mechanisms, 2006
Autoimmune uveitis is a group of HLA-associated inflammatory diseases of the eye, which can cause blindness. Patients exhibit cellular and humoral responses to immunologically privileged antigens resident in the eye. Animal models of uveitis, induced with these retinal antigens, serve an important role in studying disease mechanisms and therapies.
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