Results 11 to 20 of about 436,604 (311)

Microbiome and Autoimmune Uveitis [PDF]

Frontiers in Immunology, 2019
Commensal microbes affect all aspects of immune development and homeostasis in health and disease. Increasing evidence points to the notion that the gut commensals impact not only intestinal diseases but also diseases in tissues distant from the gut ...
Reiko Horai, Rachel R. Caspi
doaj   +4 more sources

Autoimmune uveitis: study of treatment therapies [PDF]

Einstein (São Paulo), 2010
Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues.
Alessandra Gonçalves Commodaro, Luciana de Deus Vieira de Moraes, Denise Vilarinho Tambourgi, Rubens Belfort Jr., Osvaldo Augusto Sant’Anna, Luiz Vicente Rizzo   +5 more
doaj   +8 more sources

Rat models of autoimmune uveitis [PDF]

Ophthalmic Research, 2008
Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Diedrichs-Moehring, Maria, Thurau, Stephan R., Wildner, Gerhild   +2 more
core   +5 more sources

Autoimmune Uveitis. Review

Oftalʹmologiâ, 2019
For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis.
A. N. Plekhanov, A. S. Fomina, O. P. Sverkunova, J. V. Ivanova   +3 more
doaj   +3 more sources

Autoimmunity, Autoinflammation, and Infection in Uveitis [PDF]

American Journal of Ophthalmology, 2018
Funding/Support: No funding or grant support. Financial Disclosures: John V. Forrester has received an honorarium for lecturing from Janssen (London, UK). Lucia Kuffova has undertaken consultancy work for Abbvie (London, UK). Andrew D.
Dick, Andrew D., Forrester, John V., Kuffova, Lucia   +2 more
core   +10 more sources

Autoimmune and autoinflammatory mechanisms in uveitis [PDF]

Seminars in Immunopathology, 2014
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
A Amadi-Obi, A Arida, A Cortes, A Fox, A Jager, A Peters, A Rothova, AC Anderson, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AG Commodaro, AG Commodaro, AJ St. Leger, AK Denniston, AK Denniston, AL Oberg, Andrew D. Dick, B Bodaghi, B Engelhardt, BJ Raveney, BJ Raveney, BJ Raveney, BS Sheridan, C Broderick, C Terrada, C-C Chan, CC Murphy, CEI Janssen, Chi-Chao Chan, CJ Calder, CJ Chu, CJ Chu, D Atan, D Atan, D Atan, D Atan, D Banerjee, D Luger, D Perra, DA Carter, DA Copland, DA Copland, DA Copland, DA Copland, DA Jabs, DC Wraith, DF Martin, DJ Hankey, DJ Kilmartin, DL Turner, E Furusato, EB Gouveia, EC Kerr, EC Kerr, ED Mandelcorn, EF Foxman, EF Remmers, EJ Wherry, F An, F Chen, G Geri, GJ Wright, GJ Wright, GR Wallace, H Keino, H Mielants, H. Nida Sen, HL Rosenzweig, HL Rosenzweig, HL Rosenzweig, HM Cherwinski, HN Sen, IJ Crane, J Bauer, J Candia, J Chen, J Correale, JA Todd, JB Fordham, JC Wei, JF Bach, JJ Kuiper, JP Sherlock, JT Rosenbaum, JV Forrester, JV Forrester, JV Forrester, JV Forrester, K Gocho, KG Anderson, KH Sonoda, KM Murphy, KM Murphy, L Jostins, L Mao, Lai Wei, Lindsay B. Nicholson, LK Grange, LK Mackay, LM Wakim, LM Wakim, LP Schewitz, LV Rizzo, M Chen, M Cordero-Coma, M Deckert, M Greter, M Khairallah, M Pepper, MC Jenmalm, MG Netea, MJ Mattapallil, MJ Robertson, MS Suttorp-Schulten, N Hashida, N Mizuki, N Taylor, N Yosef, NA Rao, O Tomkins-Netzer, P Kivisäkk, P Yang, P Zamiri, PA Kurz, PB Medawar, PP Sfikakis, R Banchereau, R Gold, R Plumlee Courtney, R Ramesh, R Shechter, R Zhang, R Zhou, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, Richard W. Lee, RJ Snelgrove, RK Agarwal, RM Hoek, Robert B. Nussenblatt, RP Nair, RR Caspi, RR Caspi, RR Caspi, RR Caspi, RW Darrell, RW Lee, RW Lee, RW Lee, RW Read, RW Read, S Horie, S Hou, S Hou, S Jawad, S Ohno, S Ooka, S Preston, S Sugita, S Sugita, S Sugita, S Sugita, S Yeh, S Zhang, SA Ramsey, SB Su, SC Bendall, SC Teoh, SJ Morrison, SL Masters, SM Islam, SM Sharma, SM Whitcup, SR Boyd, SR Taylor, SR Thurau, SR Thurau, SW McPherson, T Lambe, T Yoshimura, TA Manolio, TM Martin, U Kaufmann, VL Calder, W Chi, W Chi, WF Hickey, WW Soon, Y Fei, Y Kirino, Y Okunuki, Y Peng, Y Usui, YH Lee, Z Li, Z Tu   +203 more
core   +6 more sources

CTLA-4 expression on tregs is needed for suppression of autoimmune uveitis [PDF]

Scientific Reports
Uveitis is a leading cause of blindness in the world and autoimmune uveitis is an ocular tissue specific autoimmune disease. Utilizing experimental autoimmune uveitis (EAU), we can interrogate different immune responses in the mouse that are relevant to ...
Minjun Ahn, John Dostal, Priya Hegde, Darren J. Lee   +3 more
doaj   +2 more sources

Interleukin 35-Producing Exosomes Suppress Neuroinflammation and Autoimmune Uveitis

Frontiers in Immunology, 2020
Corticosteroids are effective therapy for autoimmune diseases but serious adverse effects preclude their prolonged use. However, immune-suppressive biologics that inhibit lymphoid proliferation are now in use as corticosteroid sparing-agents but with ...
Minkyung Kang, Jin Kyeong Choi, Jin Kyeong Choi, Yingyos Jittayasothorn, Charles E. Egwuagu   +4 more
doaj   +2 more sources

Circadian Rhythm Disruption Exacerbates Autoimmune Uveitis: The Essential Role of PER1 in Treg Cell Metabolic Support for Stability and Function [PDF]

Advanced Science
Circadian rhythm plays a critical role in the progression of autoimmune diseases. While our previous study demonstrated the therapeutic effects of melatonin in experimental autoimmune uveitis, the involvement of circadian rhythm remained unclear. Using a
Wenjie Zhu, Guanyu Chen, Zhiqiang Xiao, Minzhen Wang, Zhuang Li, Yuxun Shi, Xiaohui Luo, Zuoyi Li, Haixiang Huang, Xiaoqing Chen, Lingyi Liang, Dan Liang   +11 more
doaj   +2 more sources

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis. [PDF]

Animal Model Exp Med
Shome A, Rupenthal ID, Niederer RL, Mugisho OO.   +3 more
europepmc   +2 more sources