Results 61 to 70 of about 436,604 (311)
Systematic review of studies comparing infliximab and adalimumab in autoimmune uveitis
BMJ Open Ophthalmology, 2023 Objective This study aimed to review effectiveness studies comparing two biological anti-tumour necrosis factor agents, adalimumab (ADA) and infliximab (IFX), in the management of autoimmune uveitis.Methods A systematic search was conducted across PubMed,
Nicholas Beare +2 more
doaj +1 more source
Experimental autoimmune uveitis and other animal models of uveitis: An update
Indian Journal of Ophthalmology, 2015 Over the past several decades, animal models of autoimmune uveitis directed at eye-specific antigens (Ags) have been developed. These have allowed researchers to understand the basic mechanisms that lead to these diseases and also recently helped the ...
Svati Bansal +3 more
doaj +1 more source
HLA-B27 Positivity: associated health implications [PDF]
, 2011 HLA-B27 positivity makes the onset of autoimmune diseases such as uveitis, ankylosing spondylitis and Crohn's disease more likely to occur. Ankylosing spondylitis and Crohn's disease are two types of HLA-B27 positive diseases that demonstrate a direct ...
Cox, C. L. +4 more
core +1 more source
Anatomy & Cell Biology, 2022 Experimental autoimmune uveitis (EAU), an animal model of human uveitis, is characterized by infiltration of autoimmune T cells in the uvea as well as in the retina of susceptible animals.
Jeongtae Kim +5 more
semanticscholar +1 more source
Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha). [PDF]
, 2009 Matrix metalloproteinases (MMPs) have a crucial function in migration of inflammatory cells into the central nervous system (CNS). Levels of MMP-9 are elevated in multiple sclerosis (MS) and predict the occurrence of new active lesions on magnetic ...
Du, Sienmi +6 more
core +3 more sources
Experimental and Molecular Medicine, 2022 We aimed to characterize the vascular phenotypes of an experimental autoimmune retinal uveitis (EAU) model induced by interphotoreceptor retinoid-binding protein (IRBP) using multimodal imaging techniques.
Jee Myung Yang +11 more
semanticscholar +1 more source
Gender and uveitis in patients with multiple sclerosis. [PDF]
, 2014 Multiple sclerosis (MS), a demyelinating disease of the central nervous system, is more commonly seen in women. It has been associated with both anterior and intermediate uveitis as well as retinal vasculitis.
Goldstein, Debra A, Gordon, Lynn K
core +3 more sources
Genes and Diseases, 2022 Uveitis, a vision-threatening inflammatory disease worldwide, is closely related to resident microglia. Retinal microglia are the main immune effector cells with strong plasticity, but their role in uveitis remains unclear.
Siyuan He +7 more
semanticscholar +1 more source
Rodent Models of Experimental Autoimmune Uveitis [PDF]
, 2012 The model of experimental autoimmune uveitis (EAU) in mice and in rats is described. EAU targets immunologically privileged retinal antigens and serves as a model of autoimmune uveitis in humans as well as a model for autoimmunity in a more general sense.
Rajeev K, Agarwal +2 more
openaire +4 more sources
Osteopontin and fibronectin levels are decreased in vitreous of autoimmune uveitis and retinal expression of both proteins indicates ECM re-modeling. [PDF]
PLoS ONE, 2011 Autoimmune uveitis is an intraocular inflammation that arises through autoreactive T-cells attacking the inner eye, eventually leading to blindness. However, the contributing molecular pathomechanisms within the affected tissues remain as yet elusive ...
Cornelia A Deeg +4 more
doaj +1 more source