Results 111 to 120 of about 207,009 (370)
The SARS-CoV-2 as an instrumental trigger of autoimmunity
Autoimmunity Reviews, 2021 A. Dotan +5 more
semanticscholar +1 more source
T cell exhaustion, costimulation and clinical outcome in autoimmunity and infection
Nature, 2015 The clinical course of autoimmune and infectious disease varies greatly, even between individuals with the same condition. An understanding of the molecular basis for this heterogeneity could lead to significant improvements in both monitoring and ...
E. McKinney +4 more
semanticscholar +1 more source
Modeling the influence of TH1 and TH2 type cells in autoimmune diseases [PDF]
arXiv, 2000 A sharp TH1/TH2 dichotomy has often been used to define the effects of cytokines on autoimmune diseases. However contradictory results in recent research indicate that the situation may be more complex. We build here a simple mathematical model aimed at settling the contradictions.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Febrile infection related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus with immune dysregulation as a potential pathologic mechanism. Despite promising results from second‐line immunomodulators, approximately 30% remain refractory to treatment.
Kristen S. Fisher +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACTCavin‐4 was identified as a potential autoantigen for immune‐mediated rippling muscle disease (iRMD). To validate this, we developed and tested various immunoassays, including a cell‐based assay (CBA), cavin‐4 recombinant protein ELISA, and multi‐peptide ELISA. Among 19 iRMD patients, all exhibited muscle rippling, and 13 had percussion‐induced
Reghann G. LaFrance‐Corey +13 more
wiley +1 more source
Recent advances in mast cell activation and regulation [version 1; peer review: 2 approved]
F1000Research, 2020 Mast cells are innate immune cells that intersect with the adaptive immunity and play a crucial role in the initiation of allergic reactions and the host defense against certain parasites and venoms.
Hwan Soo Kim +3 more
doaj +1 more source
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi +7 more
wiley +1 more source
Pharmaceutics, 2015 Clinical studies with montelukast show variability in effect and polymorphic OATP2B1-dependent absorption has previously been implicated as a possible cause. This claim has been challenged with conflicting data and here we used OATP2B1-transfected HEK293
Marie Brännström +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with multiple sclerosis (pwMS) may require a high level of daily assistance both for indoor and outdoor activities. Usually, relatives or friends provide daily support to MS patients who have lost personal autonomy. Several factors such as disability level and disease duration may affect the burden of care in caregivers of ...
Giuseppe Schirò +9 more
wiley +1 more source
Autoimmunity and autoimmune disease [PDF]
Nephrology Dialysis Transplantation, 2001 Katsorida, ME, Moutsopoulos, HM
openaire +3 more sources