Results 131 to 140 of about 339,261 (412)
Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]
, 2014 Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Bella +31 more
core +2 more sources
Arthritis Care &Research, EarlyView.Objective This study analyzed longitudinal trajectories of soluble Flt1 (sFlt1) levels, placenta growth factor (PlGF) levels, and sFlt1:PlGF ratios in a cohort of pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14–18, 24–26, 30–32, 34–36, and 38–40 weeks), stored at −80°C, and evaluated for serum levels ...
Nilson R. de Jesús +7 more
wiley +1 more source
MicroRNA-155—at the critical interface of innate and adaptive immunity in arthritis [PDF]
, 2018 MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a changing environment by modulating the cell transcriptome. MiR-155 is a multifunctional miRNA enriched in cells of the immune system and is indispensable for the immune ...
Barbara Tolusso +8 more
core +2 more sources
Metabolic Consequences of Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry +2 more
wiley +1 more source
Antibodies, 2017 Premature, accelerated onset of atherothrombotic disease is prevalent in patients with systemic lupus erythematosus (SLE). Most, if not all, atherothrombotic diseases are likely to involve platelets and complement.
Chau-Ching Liu +4 more
doaj +1 more source
Modeling the influence of TH1 and TH2 type cells in autoimmune diseases [PDF]
arXiv, 2000 A sharp TH1/TH2 dichotomy has often been used to define the effects of cytokines on autoimmune diseases. However contradictory results in recent research indicate that the situation may be more complex. We build here a simple mathematical model aimed at settling the contradictions.
arxiv
T cell exhaustion, costimulation and clinical outcome in autoimmunity and infection
Nature, 2015 The clinical course of autoimmune and infectious disease varies greatly, even between individuals with the same condition. An understanding of the molecular basis for this heterogeneity could lead to significant improvements in both monitoring and ...
E. McKinney +4 more
semanticscholar +1 more source
Review of presentations at the 6th European Lupus Meeting 3-5 March 2005. [PDF]
, 2005 The 6th European Lupus Meeting was held at the Royal College of Physicians of London and was attended by 450 delegates. The conference brought together leading speakers from Europe and North America who reviewed current knowledge and exciting new ...
Bowman, SJ +3 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objectives Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE), and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim +11 more
wiley +1 more source
Anti-Idiotypic Agonistic Antibodies: Candidates for the Role of Universal Remedy
Antibodies, 2020 Anti-idiotypic antibodies (anti-IDs) were discovered at the very beginning of the 20th century and have attracted attention of researchers for many years. Nowadays, there are five known types of anti-IDs: α, β, γ, ε, and δ. Due to the ability of internal-
Aliya K. Stanova +5 more
doaj +1 more source