Results 161 to 170 of about 349,570 (384)
Advanced Biology, EarlyView.HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang +6 more
wiley +1 more source
Autoimmunity and the retina. II. Raised serum IgM levels in retinitis pigmentosa. [PDF]
, 1973 A H Rahi
openalex +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Advanced Biology, EarlyView.Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang +8 more
wiley +1 more source
Association of defective feedback suppressor t cell activity with autoimmunity in nzb mice [PDF]
, 1978 Richard K. Gershon +3 more
openalex +1 more source
Advanced Biology, EarlyView.This study optimized a cell‐based ELISA for HIT antibody detection using PF4‐coated breast cancer cells (MDA‐MB‐231). Enhanced binding was observed at 50 mM NaCl and 4% paraformaldehyde fixation. Live MDA‐MB‐231 and HCT‐116 cells demontrated superior sensitivity and specificity, providing a promising platelet‐free alternative for clinical HIT diagnosis.
Li‐Yu Chen +4 more
wiley +1 more source
Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]
, 2012 Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
World Journal of Neuroscience, 2017 Autoimmune encephalitis is a severe inflammatory disorder of the brain with diverse causes and a complex differential diagnosis. Recent advances in the past decade have led to the identification of new syndromes and biological markers of limbic encephalitis, the commonest presentation of autoimmune encephalitis.
openaire +3 more sources
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source