Results 171 to 180 of about 296,707 (334)

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Comprehensive clinical and immunologic characterization of Wiskott-Aldrich syndrome in Iran: a 10-year cohort study. [PDF]

BMC Immunol
Esmaeilzadeh H, Gholami MA, Dehghani SS, Nabavizadeh H, Alyasin S, Rezaei N, Delavari S, Abolhassani H, DorriMoghaddam F, Ghasemi F.   +9 more
europepmc   +1 more source

Impact of Enoxaparin on Maternal and Fetal Outcomes in In Vitro Fertilization (IVF) Pregnancies With Thyroid Autoimmunity: A Real-World, Single-Center, Retrospective, Observational Study [PDF]

G. A. Rama Raju, Ponnada Sravani, Pranati Mahapatro, Aruna Kovvuri, Vishal Dave, Vivek Sharma, Deepak Bunger   +6 more
openalex   +1 more source

Targeting Metabolism as a Novel Therapeutic Approach to Autoimmunity, Inflammation, and Transplantation [PDF]

, 2017
Ian A. Bettencourt, Jonathan D. Powell
openalex   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

The 2025 Nobel Prize in Physiology or Medicine - a bridge to peripheral immune tolerance. [PDF]

J Clin Invest
Bluestone JA.
europepmc   +1 more source

Dextran Sulfate Protects Pancreatic β-Cells, Reduces Autoimmunity and Ameliorates Type 1 Diabetes

, 2020
Ada Admin, Geming Lu, Francisco Rausell-Palamos, Jiamin Zhang, Zihan Zheng, Tuo Zhang, Shelley Valle, Carolina Rosselot, Cecilia Berrouet, P. Condé, Matthew P. Spindler, John Graham, Dirk Homann, Adolfo García‐Ocaña   +13 more
openalex   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity. [PDF]

Nat Metab
Ott R, Zapardiel-Gonzalo J, Kreitmaier P, Casteels K, Hommel A, Kordonouri O, Elding Larsson H, Szypowska A, Vatish M, Zeggini E, Knopff A, Winkler C, Ziegler AG, Bonifacio E, Hummel S.   +14 more
europepmc   +1 more source