Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives
Advanced Materials, EarlyView.Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin +6 more
wiley +1 more source
The impact of familial autoimmunity and familial lupus on the clinical presentations and disease outcomes of SLE patients in the United Arab Emirates. [PDF]
BMC RheumatolAl Dhaheri A +8 more
europepmc +1 more source
The Bionic Interface: Considering the Material Mediated Electrical Stimulation of Stem Cells
Advanced Materials, EarlyView.Electrical stimulation directs stem cell fate in tissue engineering. Cellular responses are influenced by membrane properties, intrinsic cell state, material charge‐transport characteristics, and the applied electrical signal. Additionally, a material’s ability to inject, store, and redistribute charge further modulates these responses.
Kaiwen Zhang +6 more
wiley +1 more source
Reconsidering the diagnostic potential of thyroperoxidase autoantibodies in chronic spontaneous urticaria. [PDF]
World Allergy Organ JAphale P, Shekhar H, Dokania S.
europepmc +1 more source
Advanced Therapeutics, EarlyView.This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli +5 more
wiley +1 more source
Central nervous system targeted autoimmunity causes regional atrophy: a 9.4T MRI study of the EAE mouse model of Multiple Sclerosis [PDF]
, 2019 Alastair Hamilton +6 more
openalex +1 more source
Advanced Science, EarlyView.Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
S-TIR-ring up TLR7 and TLR9: signaling domain substitutions clarify the TLR paradox. [PDF]
J Clin InvestTachó-Piñot R, Vinuesa CG.
europepmc +1 more source
Diminished regulatory T cells in cutaneous lesions of thymoma-associated multi-organ autoimmunity: a newly described paraneoplastic autoimmune disorder with fatal clinical course [PDF]
, 2011 Toshiaki Hanafusa +9 more
openalex +1 more source