Results 191 to 200 of about 296,707 (334)

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Autoimmune Thyroid Disease and Female Fertility: Does Anti-TPO Accelerate Ovarian Aging? [PDF]

J Clin Med
Arlıer S, Kükrer S.
europepmc   +1 more source

The role of autoimmunity in women with type 1 diabetes and adverse pregnancy outcome: A missing link

, 2019
Bart Groen, Thera P. Links, Paul P. van den Berg, Paul de Vos, Marijke M. Faas   +4 more
openalex   +1 more source

Autoimmunity and autoinflammation in pathogenesis of immunoinflammatory diseases

, 2020
Н П Шилкина, I. V. Masina, I. V. Dryazhenkova, Anatoliy Vinogradov, I. E. Yunonin   +4 more
openalex   +2 more sources

Lnc‐HZ05 Suppresses Trophoblast Cell Migrasome Formation by Disrupting TGFβ2 Pathway in Unexplained Recurrent Miscarriage

Advanced Science, EarlyView.
TGFβ2 signaling‐mediated migration/invasion and migrasome formation are suppressed in recurrent miscarriage (RM) versus healthy control villous tissues and are negatively associated with unexplained RM. In mechanism, TGFβ2 promotes trophoblast cell migration/invasion and migrasome formation, all of which are suppressed by lnc‐HZ05. In details, lnc‐HZ05
Weina Chen, Ying Zhang, Zimeng Zhao, Yang Yang, Geng Guo, Yi Sun, Tao Zhang, Zhihong Zhang, Liqin Zeng, Wenxin Huang, Qingjun Shen, Ruining Han, Zhaohui He, Depeng Zhao, Huidong Zhang   +14 more
wiley   +1 more source

Islet autoimmunity and progression to type 1 diabetes in the Finnish DIPP study: comparison between genetically susceptible children with and without an affected first-degree relative. [PDF]

Diabetologia
Kuusela S, Koskenniemi JJ, Valtanen T, Pokka T, Härkönen T, Ilonen J, Lempainen J, Kyrönniemi A, Toppari J, Knip M, Keskinen P, Veijola R.   +11 more
europepmc   +1 more source

Faculty Opinions recommendation of Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential.

, 2020
Khashayar Sakhaee
openalex   +2 more sources

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, EarlyView.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Role of thyroid autoimmunity independent of thyroid hormone levels in pulmonary function decline: A population-based study in euthyroid adults. [PDF]

PLoS One
Sung KH, Kwak J, Kim MK, Lim DJ, Lee JM, Chang SA, Lee J.   +6 more
europepmc   +1 more source

Development of Central Nervous System Autoimmunity Is Impaired in the Absence of Wiskott-Aldrich Syndrome Protein

, 2014
Marita Bosticardo, Silvia Musio, Elena Fontana, Stefano Angiari, Elena Draghici, Gabriela Constantin, Pietro Luigi Poliani, Rosetta Pedotti, Anna Villa   +8 more
openalex   +2 more sources