Results 221 to 230 of about 296,707 (334)

Effects of deviating the Th2-response in murine mercury-induced autoimmunity towards a Th1-response

, 2003
Bo Häggqvist, Per Hultman
openalex   +2 more sources

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Cigarette Smoking: A Modifiable Environmental Factor in the Pathogenesis of Rheumatoid Arthritis. [PDF]

JMA J
Masuko K.
europepmc   +1 more source

Thyrotropin and growth promoting immunoglobulin (TGI) of FRTL-5 cells have no growth stimulating activity on human thyroid epithelial cell cultures [PDF]

, 1987
Bay, V., Dwenger, M., Engel, U., Fenzi, G. F., Ingbar, S. H., Mansky, T., Mckenzie, J. M., Pinchera, Aldo, Scriba, Peter Christian, Wenzel, B. E.   +9 more
core  

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Detection of autoantibodies in severe COVID-19 patients two years after hospital discharge. [PDF]

Braz J Med Biol Res
Hi EMB, Bianchi CCR, Gritte RB, Klauss PHA, Leal NFSM, Oliveira IS, Barros MFCB, Soriano FG, Curi R, Machado MCC.   +9 more
europepmc   +1 more source

Drug-Induced Autoimmunity

, 2016
Douglas M. Templeton, Michael Schwenk, Reinhild Klein, John H. Duffus   +3 more
openalex   +2 more sources

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Latent autoimmune diabetes in youth. [PDF]

Front Immunol
Sun Q, Yang M, Jing Y, Meng L, Zhang C, Ruan J, Wu N.   +6 more
europepmc   +1 more source