Results 221 to 230 of about 207,009 (370)

SENP3 Drives Abdominal Aortic Aneurysm Development by Regulating Ferroptosis via De‐SUMOylation of CTH

open access: yesAdvanced Science, EarlyView.
In this study, it is proposed that SENP3 accumulates in macrophages of aneurysmal aortic tissues, which promotes macrophage ferroptosis and inflammation via regulation of CTH de‐SUMOylation. Abstract Abdominal aortic aneurysm (AAA) is a high‐risk inflammatory disorder. SENP3, a SUMO2/3‐specific protease, is closely involved in the development of cancer.
Long Chen   +15 more
wiley   +1 more source

Polyautoimmunity Reflecting Immune Dysregulation in Common Variable Immunodeficiency. [PDF]

open access: yesBiomedicines
Danieli MG   +8 more
europepmc   +1 more source

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

open access: yesCell, 2016
T. Vatanen   +24 more
semanticscholar   +1 more source

CXCL13 Damages Blood Spinal Cord Barrier by Promoting RNF6/Sqstm1‐Ubiquitination Induced Autophagy in Experimental Allergic Encephalomyelitis

open access: yesAdvanced Science, EarlyView.
In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han   +10 more
wiley   +1 more source

Clinical overview on RASopathies

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Human immunodeficiency virus—associated vitiligo: Expression of autoimmunity with immunodeficiency?

open access: green, 1987
Madeleine Duvic   +3 more
openalex   +1 more source

The multiple pathways to autoimmunity

open access: yesNature Immunology, 2017
A. Theofilopoulos, D. Kono, R. Baccala
semanticscholar   +1 more source

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