Results 231 to 240 of about 296,707 (334)

Autoimmune Hepatitis.

Internal Medicine, 1993
M, Zeniya, G, Toda
openaire   +4 more sources

Smohaze‐Upregulated RFWD3 Competes with TRIM24 to Stabilize TREX1 and Reduce Cytosolic dsDNA in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi, Yu‐Ke Shen, Meng‐Yao Lv, Yu Sun, Yong‐Fang Lin, Zheng Wang, Xiao‐Liang Jie, Zheng Liu, Yang‐Tong Liu, Yang‐Xin Fu, Zhenhua Ren, Gui‐Zhen Wang, Guang‐Biao Zhou   +12 more
wiley   +1 more source

Editorial: Autoimmunity: novel insights and future perspectives. [PDF]

Front Immunol
Neagu M, Ilie MA, Mihai A, Caruntu C.
europepmc   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Inflammasome activation and accelerated immune aging in autoimmune disorders. [PDF]

Front Aging
Mittal R, Saavedra D, Mittal M, Lemos JRN, Hirani K.   +4 more
europepmc   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

Chronic Stress and Autoimmunity: The Role of HPA Axis and Cortisol Dysregulation. [PDF]

Int J Mol Sci
Nunez SG, Rabelo SP, Subotic N, Caruso JW, Knezevic NN.   +4 more
europepmc   +1 more source

The role of autoimmunity in premature ovarian failure.

, 2015
Mahbod Ebrahimi, Firouzeh Akbari Asbagh
openalex   +1 more source

Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol

Sandra Hummel, Alexandra Käßl, Stefanie Arnolds, Peter Achenbach, Reinhard Berner, Kristina Casteels, Heikki Hyöty, Olga Kordonouri, Helena Elding Larsson, Markus Lundgren, M. Loredana Marcovecchio, Catherine Owen, Markus Pfirrmann, Steve Robson, Agnieszka Szadkowska, Agnieszka Szypowska, Timothy Tree, Andreas Weiß, Anette-Gabriele Ziegler, Ezio Bonifacio   +19 more
openalex   +1 more source

A novel missense variant in TNFAIP3 associated with autoimmunity reveals the contribution of STAT1/mTOR pathways [PDF]

Judith Potjewijd, Hans J. P. M. Koenen, Caspar I. van der Made, Esther van Rijssen, Xuehui He, Renée Ysermans, Liset Ungethüm, Ruud Theunissen, Leon J. Schurgers, Jan Damoiseaux, Pieter van Paassen, Ruben L. Smeets   +11 more
openalex   +1 more source