Results 231 to 240 of about 339,261 (412)

Anti-RNP monoclonal antibodies derived from a mouse strain with lupus-like autoimmunity. [PDF]

, 1982
Peter B. Billings, Richard Allen, Fred C. Jensen, Sallie O. Hoch   +3 more
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Postnatal disappearance of self-reactive (V beta 6+) cells from the thymus of Mlsa mice. Implications for T cell development and autoimmunity. [PDF]

, 1989
R Schneider, Rosemary K. Lees, Thierry Pedrazzini, Rolf M. Zinkernagel, Hans Hengartner, H. Robson MacDonald   +5 more
openalex   +1 more source

Implications of macrophage polarization in autoimmunity

Immunology, 2018
S. C. Funes, M. Ríos, J. Escobar-Vera, A. Kalergis   +3 more
semanticscholar   +1 more source

Autoimmunity

Current Opinion in Immunology, 1991
openaire   +2 more sources

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Advanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou   +4 more
wiley   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Diabetes Mellitus and Thyroid Autoimmunity in Gonadal Dysgenesis

, 1973
J. Van Campenhout, A. Antaki, E Rasio
openalex   +1 more source

A specific IgG in Graves' ophthalmopathy and its relation to retro-orbital and thyroid autoimmunity. [PDF]

, 1984
P. Kendall‐Taylor, Stephanie A. Atkinson, Menna Holcombe   +2 more
openalex   +1 more source

Bioorthogonal Reaction of o‐Quinone with Furan‐2(3H)‐One for Site‐Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes

Advanced Science, EarlyView.
A site‐selective, efficient, and mild tyrosine conjugation via tyrosinase oxidation and nucleophilic addition, allowing for site‐selective functionalization of peptides, recombinant proteins, and IgGs. Site‐selective mono‐functionalization of IgGs at Y296 enables the construction of immunoliposomes.
Hongfei Chen, Zhiyi Xu, Yishu Bao, Farshad Shiri, Dingdong Yuan, Yuke Hu, Biquan Li, Bin Zeng, Xiaojing Li, Hao Kong, Zikang Wang, Wilson Chun‐Yu Lau, Zhenyang Lin, Jiang Xia   +13 more
wiley   +1 more source