Results 261 to 270 of about 349,570 (384)

Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus

Advanced Science, EarlyView.
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu, Qianmin Ou, Qianhui Ren, Zhengshi Li, Hongcheng Chen, Fangcao Lei, Xueli Mao, Songtao Shi, Zetao Chen, Wei Teng   +9 more
wiley   +1 more source

Narrowing Down Key Players in Autoimmunity via Single-Cell Multiomics. [PDF]

Eur J Immunol
Gjurgjaj A, Conde CD.
europepmc   +1 more source

Endogenous systemic IFN-gamma has a protective role against ocular autoimmunity in mice. [PDF]

, 1994
Rachel R Caspi, Christina Chan, B G Grubbs, P. B. Silver, Barbara Wiggert, C F Parsa, Sina Bahmanyar, Alfons Billiau, Hubertine Heremans   +8 more
openalex   +1 more source

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

Advanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu, Lu Diao, Jin Wang, Ao Zhu, Xianlan Chen, Yan Zheng, Yuhan Liu, Kang Hu, Jiashan Zhu, Cheng Ding, Chang Li, Yunzhi Pan, Jun Zhao, Mi Liu   +13 more
wiley   +1 more source

Commentary: Cancer in connective tissue disease. [PDF]

Front Immunol
Chen J.
europepmc   +1 more source

Cuproptosis Signature Would Reveal the Acute‐Remitting Pattern in Patients with Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
Neuromyelitis optica spectrum disorder (NMOSD) has distinct acute‐remitting courses but lacks biomarkers for predicting relapse. Recent studies found cuproptosis‐related genes affect its course, and a model built accordingly can predict relapse to aid intervention.
Peidong Liu, Ruoyu Li, Xinlin Wang, Hui Li, Huiru Hu, Ang Shen, Wenping Zhu, Jiali Pan, Yanmeng Xing, Weiming Xia, Henan Jiao, Di Chen, Lixin Wu, Li Liu, Ju Liu, Bin Yu, Xianzhi Liu, Hongbo Liu   +17 more
wiley   +1 more source

Thymic central tolerance takes centre stage in autoimmune disease. [PDF]

Lancet Reg Health West Pac
Mulic-Al Bunni S, Handel AE.
europepmc   +1 more source

Differential Effects of X‐Irradiation and Cyclosporin‐AAdministration on the Thymus with Respect to theGeneration of Cyclosporin‐A‐Induced Autoimmunity [PDF]

, 1994
Leo J.J. Beijleveld, Jan Damoiseaux, Peter J.C. van Breda Vriesman   +2 more
openalex   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Pathogenesis of Autoimmunity/Systemic Lupus Erythematosus (SLE). [PDF]

Cells
Shiozawa S.
europepmc   +1 more source