Results 281 to 290 of about 349,570 (384)

CAR T cells for infection, autoimmunity and allotransplantation

Nature reviews. Immunology, 2018
C. Maldini, Gavin I. Ellis, J. Riley
semanticscholar   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Anti-neutrophil Cytoplasmic Antibody-Associated Vasculitis Presenting With Disseminated Streptococcus constellatus Pyogenic Infection. [PDF]

Cureus
Karypidou E, Mademlis C, Adamichou C, Skouvaklidou E, Mavridis C, Zarras C, Flegkas P, Simoulidou E, Kefas A, Chatzimichailidou S, Sarvani A, Koufakis T, Damianidis G, Pyrpasopoulou A.   +13 more
europepmc   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

IFN-α Neutralizing Antibodies Distinguish LADA From Early-onset Type 1 Diabetes.

J Clin Endocrinol Metab
Amendolara R, D'Onofrio L, Sessa RL, Di Giulio S, Mignogna C, Coraggio L, Schirano R, Zampetti S, Malandrucco I, Pozzilli P, Giannini G, Maddaloni E, Buzzetti R.   +12 more
europepmc   +1 more source

Immunohistochemical characterization of the oral lesions in MRL/1 mouse (autoimmunity and lymphoproliferation).

, 1987
Yoshihisa Watanabe, Hideyuki Miyamoto, Toshitaka Yamaoka, Isao Kondô, Taro Hisada   +4 more
openalex   +2 more sources

A cellular and molecular view of T helper 17 cell plasticity in autoimmunity.

Journal of Autoimmunity, 2018
R. Stadhouders, E. Lubberts, R. Hendriks
semanticscholar   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Autoimmune Polyglandular Syndrome Type 3 and Overlapping Autoimmune Endocrinopathies: A Case Report. [PDF]

Cureus
Nagarajan DR, Mani Jacob D, Ottu Para NK.   +2 more
europepmc   +1 more source

Clinical significance and immunobiology of IL-21 in autoimmunity.

Journal of Autoimmunity, 2019
Di Long, Yongjian Chen, Haijing Wu, Ming Zhao, Q. Lu   +4 more
semanticscholar   +1 more source