Results 301 to 310 of about 349,570 (384)

Micro-chimerism: from evolution to revolution. [PDF]

Semin Immunopathol
Urbschat C, Arck PC.
europepmc   +1 more source

Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

Proceedings of the National Academy of Sciences of the United States of America, 2017
Guoyan Zhao, T. Vatanen, L. Droit, A. Park, A. Kostic, Tiffany W. Poon, H. Vlamakis, Heli Siljander, T. Härkönen, A. Hämäläinen, A. Peet, V. Tillmann, J. Ilonen, David Wang, M. Knip, R. Xavier, H. Virgin   +16 more
semanticscholar   +1 more source

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

Advanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang, Yongqi Wu, Ke Hou, Yiwen Zhang, Lin Chen, Muyao Yang, Zhehui Jin, Yongchao Xu, Yingjie Zhang, Yinli Cai, Jiayu Zhao, Shisheng Sun   +11 more
wiley   +1 more source

Editorial: Innate immune dysregulation: a driving force of autoimmunity and chronic inflammation. [PDF]

Front Immunol
Akbarzadeh R, Humrich JY, Németh T, Amber KT.   +3 more
europepmc   +1 more source

Autoimmunity to a 28–30 kD cell membrane DNA binding protein: occurrence in selected sera from patients with SLE and mixed connective tissue disease (MCTD)

, 1991
Robert M. Bennett, Ken Cornell, M J MERRITT, Antony C. Bakke, Ping‐Ning Hsu, Steven H. Hefeneider   +5 more
openalex   +2 more sources

A Complementarity‐Based Approach to De Novo Binder Design

Advanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko, Valeriia Hatskovska, Murray Coles, Narges Aghaallaei, Natalia Pashkovskaia, Natalia Borbarán‐Bravo, Matteo Pilz, Philip Bucher, Mareike Volz, Joana Pereira, Marcus D. Hartmann, Ghazaleh Tabatabai, Judith Feucht, Stefan Liebau, Patrick Müller, Andrei N. Lupas, Julia Skokowa, Mohammad ElGamacy   +17 more
wiley   +1 more source

Cytokine signaling defects in primary atopic diseases-an updated review. [PDF]

Front Allergy
Thakur V, Pilania RK, Sharma A, Sharma S, Mario AT, Goyal T, Sharma M, Vaitheeswaran GC, Vignesh P, Singh S, Dhaliwal M, Rawat A.   +11 more
europepmc   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source