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High-dose therapy and autologous stem cell transplantation in patients with POEMS syndrome: a retrospective study of the Plasma Cell Disorder sub-committee of the Chronic Malignancy Working Party of the European Society for Blood & Marrow Transplantation [PDF]
Haematologica, 2017 POEMS syndrome is a rare para-neoplastic syndrome secondary to a plasma cell dyscrasia. Effective treatment can control the disease-related symptom complex.
Gordon Cook +21 more
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Cells, 2022 The infusion of autograft immune effector cells directly impacts the clinical outcomes of patients treated with autologous peripheral blood hematopoietic stem cell transplantation, suggesting the possibility of an autologous graft-versus tumor cells ...
Luis F. Porrata
doaj +1 more source
Low-intensity pulsed ultrasound promotes mesenchymal stem cell transplantation-based articular cartilage regeneration via inhibiting the TNF signaling pathway [PDF]
Stem Cell Res Ther 14, 93 (2023), 2021 Background: Mesenchymal stem cell (MSC) transplantation therapy is highly investigated for the regenerative repair of cartilage defects. Low-intensity pulsed ultrasound (LIPUS) has the potential to promote chondrogenic differentiation of MSCs. However, its underlying mechanism remains unclear.
arxiv +1 more source
Cells, 2022 Autologous stem cell transplantation treatment has been viewed as a therapeutic modality to enable the infusion of higher doses of chemotherapy to eradicate tumor cells. Nevertheless, recent reports have shown that, in addition to stem cells, infusion of
Luis F. Porrata
doaj +1 more source
The Role of Autologous Stem Cell Transplantation in Amyloidosis [PDF]
ONCOLOGY, 2021 Autologous stem cell transplantation (ASCT) has been an essential part of the treatment armamentarium in light chain (AL) amyloidosis for several decades. Patients who achieve a complete hematologic response following ASCT have a long overall survival. However, only 1 randomized controlled trial compared ASCT with the standard of care used at the time,
Iuliana Vaxman, Angela Dispenzieri
openaire +3 more sources
Autologous chemotaxis at high cell density [PDF]
, 2021 Autologous chemotaxis, in which cells secrete and detect molecules to determine the direction of fluid flow, is thwarted at high cell density because molecules from other cells interfere with a given cell's signal. Using a minimal model of autologous chemotaxis, we determine the cell density at which sensing fails and find that it agrees with ...
arxiv +1 more source
Autologous Stem Cell Transplantations
Annals of Medicine, 1996 High-dose treatments with autologous stem cell support have increasingly been used to improve the treatment results of a variety of haematological and nonhaematological malignancies. High-dose treatments cause severe bone marrow injury, which can effectively be rescued with infusion of a sufficient number of stem cells. Stem cells can be collected from
Allan Rajamäki, Kari Remes
openaire +3 more sources
Haematologica, 2014 Allogeneic stem cell transplantation is the standard approach to Philadelphia chromosome positive acute lymphoblastic leukemia. We hypothesized that imatinib plus sequential chemotherapy will result in significant leukemia cell cytoreduction in patients ...
Meir Wetzler +12 more
doaj +1 more source
Stem Cells International, 2015 Aim. To evaluate whether patients with multiple myeloma at various risks can still benefit the same from autologous stem cell transplantation consolidation in the era of novel agents.
Tianmei Zeng +7 more
doaj +1 more source
Haematologica, 2009 High-dose melphalan chemotherapy and autologous peripheral blood stem cell transplantation has been shown to result in durable hematologic response and prolonged overall survival in systemic AL amyloidosis.
Saulius Girnius +6 more
doaj +1 more source