Results 31 to 40 of about 6,141,684 (256)

Epidemiology of Invasive Fungal Diseases: A 10-Year Experience in a Tertiary Pediatric Hematology–Oncology Department in Greece

Journal of Fungi
Although advances in the management of pediatric neoplasms have profoundly improved infectious disease outcomes, invasive fungal diseases (IFDs) remain a major cause of morbidity and mortality in children and adolescents with high-risk hematological ...
Eleni Moraitaki, Ioannis Kyriakidis, Iordanis Pelagiadis, Nikolaos Katzilakis, Maria Stratigaki, Georgios Chamilos, Athanasios Tragiannidis, Eftichia Stiakaki   +7 more
doaj   +1 more source

A case report of severe veno-occlusive disease following autologous stem cell transplantation successfully treated with Defibrotide

European Journal of Translational Myology, 2020
Veno-occlusive disease (VOD) is one of the complications of hematopoietic stem cell transplantation that can also be caused by high-dose chemotherapy. This complication can lead to high mortality following bone marrow transplantation.
Gholamreza Bahoush, Maryam Vafapour
doaj   +1 more source

Noninvasive in vivo tracking of mesenchymal stem cells and evaluation of cell therapeutic effects in a murine model using a clinical 3.0 T MRI [PDF]

, 2013
Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment approach for end-stage heart failure. However, little is known about the underlying mechanisms and the fate of the transplanted cells. The objective of the presented
Neef, Klaus, Drey, Florian, Choi, Yeong-Hoon, Brenkmann, Meike, Tenbrock, Arne, Wahlers, Thorsten, Treskes, Philipp, Wittwer, Thorsten, Liakopoulos, Oliver J, Ewert, Birgit, Bovenschulte, Henning, Stamm, Christof   +11 more
core   +1 more source

Tandem autologous hematopoietic stem cell transplantation for patients with multiple myeloma: a systematic review and meta-analysis

Hematology
To evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of Science and Cochrane Library databases were systematically searched, and 10 eligible ...
Hongtao Li, Yaxin Zheng, Kehai Gao, Chen Tian   +3 more
doaj   +1 more source

Loss of quiescence and impaired function of CD34+/CD38low cells one year following autologous stem cell transplantation

Haematologica, 2013
Patients who have undergone autologous stem cell transplantation are subsequently more susceptible to chemotherapy-induced bone marrow toxicity. In the present study, bone marrow primitive progenitor cells were examined one year after autologous stem ...
Carolien M. Woolthuis, Annet Z. Brouwers-Vos, Gerwin Huls, Joost Th. M. de Wolf, Jan Jacob Schuringa, Edo Vellenga   +5 more
doaj   +1 more source

Regulation of boundary cap neural crest stem cell differentiation after transplantation [PDF]

, 2009
Success of cell replacement therapies for neurological disorders will depend largely on the optimization of strategies to enhance viability and control the developmental fate of stem cells after transplantation.
Hjerling-Leffler, J, Aldskogius, Hakan, Wegner, M, Hjerling-Leffler, Jens, Kozlova, Elena N, Medvinsky, Alexander, Berens, C, Aldskogius, H, Kozlova, EN, Berens, Christian, Kanaykina, Nadezda, Sandelin, Martin, Schreiner, S, Wegner, Michael, Kanaykina, N, Sandelin, M, Liakhovitskaia, A, Medvinsky, A, Liakhovitskaia, Anna, Schreiner, Silke, Kanaykina, Nadegda,, Kozlova, Elena,, Aldskogius, Håkan,, Sandelin, Martin,, Berens, Christian,   +24 more
core   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Association of DROSHA Variants with Susceptibility and Outcomes in Childhood Acute Lymphoblastic Leukemia

Current Issues in Molecular Biology
MicroRNAs are key regulators of lymphoid differentiation, exhibiting a pivotal role in acute lymphoblastic leukemia (ALL) biology and prognosis. The initial steps of canonical miRNA biogenesis involve the microprocessor complex processing the primary ...
Ioannis Kyriakidis, Iordanis Pelagiadis, Charalampos Pontikoglou, Helen A. Papadaki, Eftichia Stiakaki   +4 more
doaj   +1 more source

Ethical and Regulatory Challenges with Autologous Adult Stem Cells:A Comparative Review of International Regulations [PDF]

, 2013
Cell and tissue-based products, such as autologous adult stem cells, are being prescribed by physicians across the world for diseases and illnesses that they have neither been approved for or been demonstrated as safe and effective in formal clinical ...
Lysaght, T, Lysaght, Tamra, Sipp, Douglas, Kerridge, I, Porter, G, Sipp, D, Porter, Gerard, Capps, Benjamin J., Kerridge, Ian, Capps, BJ, Porter, G., Kerridge, I., Sipp, D., Lysaght, T., Capps, B.J.   +14 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source