Results 21 to 30 of about 205,182 (367)

Autologous Graft-versus-Tumor Effect: Reality or Fiction?

Advances in Hematology, 2016
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell ...
Luis F. Porrata
doaj   +1 more source

Individual quality assessment of autografting by probability estimation for clinical endpoints: a prospective validation study from the European group for blood and marrow transplantation. [PDF]

, 2013
The aim of supportive autografting is to reduce the side effects from stem cell transplantation and avoid procedure-related health disadvantages for patients at the lowest possible cost and resource expenditure.
Campioni, Dc, Cuneo, A, Farge, D, Fiamenghi, C, Fruehauf, S, Hellmann, A, Johnsen, He, Knopińska, W, Lanza, F, Madrigal, A, Milone, G, Mohty, M, Passweg, J, Petriz, J, Quality Assessment of Haematopoietic Stem Cell Grafting Committee of European Blood and Marrow Transplantation Society, Ruuto, T, Spedini, P, Swierkowska-Czeneszew, M, Wahlin, A, Walewski, J   +19 more
core   +1 more source

Computational tools for assessing gene therapy under branching process models of mutation [PDF]

arXiv, 2021
Multitype branching processes are ideal for studying the population dynamics of stem cell populations undergoing mutation accumulation over the years following transplant. In such stochastic models, several quantities are of clinical interest as insertional mutagenesis carries the potential threat of leukemogenesis following gene therapy with ...
arxiv  

Novel Advancements in Three-Dimensional Neural Tissue Engineering and Regenerative Medicine [PDF]

Neural Regen. Res. 2015;10(3):352-4, 2015
Neurological diseases and injuries present some of the greatest challenges in modern medicine, often causing irreversible and lifelong burdens in the people whom they afflict. These diagnoses have devastating consequences on millions of people each year, and yet there are currently no therapies or interventions that can repair the structure of neural ...
arxiv   +1 more source

AUTOLOGOUS STEM CELL TRANSPLANTATION FOR AGGRESSIVE LYMPHOMAS

Mediterranean Journal of Hematology and Infectious Diseases, 2012
The role of high-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) in the treatment armamentarium of aggressive B- and T-cell non-Hodgkin lymphoma (NHL) is still a matter of debate. In the pre-Rituximab era, the PARMA study demonstrated the superiority of HDT/ASCT over conventional salvage chemotherapy in chemosensitive ...
Visani G, Picardi P, Tosi P, GONELLA, ROBERTA, Loscocco F, Ricciardi T, Malerba L, Guiducci B, Tomassetti S, Barulli S, Isidori A.   +10 more
openaire   +5 more sources

Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]

, 2018
Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice, Lambiase, Alessandro, Rama, Paolo, Sacchetti, Marta   +3 more
core   +1 more source

Single or tandem autologous stem-cell transplantation for first-relapsed or refractory Hodgkin lymphoma: 10-year follow-up of the prospective H96 trial by the LYSA/SFGM-TC study group

Haematologica, 2016
We assessed the long-term results of autologous stem-cell transplantation for patients with first-relapsed or refractory Hodgkin lymphoma included in the prospective Lymphoma Study Association/Société Française de Greffe de Moelle H96 trial.
David Sibon, Franck Morschhauser, Matthieu Resche-Rigon, David Ghez, Jehan Dupuis, Ambroise Marçais, Bénédicte Deau-Fischer, Reda Bouabdallah, Catherine Sebban, Gilles Salles, Pauline Brice   +10 more
doaj   +1 more source

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation [PDF]

PLoS One. 2017 Dec 1;12(12):e0187771, 2016
Alloreactivity following stem cell transplantation (SCT) is difficult to predict in patients undergoing transplantation from HLA matched donors. In this study we performed whole exome sequencing of SCT donor-recipient pairs (DRP). This allowed determination of entire library of alloreactive peptide sequences which would bind HLA class I molecules in ...
arxiv   +1 more source

A case report of severe veno-occlusive disease following autologous stem cell transplantation successfully treated with Defibrotide

European Journal of Translational Myology, 2020
Veno-occlusive disease (VOD) is one of the complications of hematopoietic stem cell transplantation that can also be caused by high-dose chemotherapy. This complication can lead to high mortality following bone marrow transplantation.
Gholamreza Bahoush, Maryam Vafapour
doaj   +1 more source

A Review of Autologous Stem Cell Transplantation in Lymphoma [PDF]

Current Hematologic Malignancy Reports, 2017
Chemotherapy remains the first-line therapy for aggressive lymphomas. However, 20-30% of patients with non-Hodgkin lymphoma (NHL) and 15% with Hodgkin lymphoma (HL) recur after initial therapy. We want to explore the role of high-dose chemotherapy (HDT) and autologous stem cell transplant (ASCT) for these patients.There is some utility of upfront ...
Irbaz Bin Riaz, Faiz Anwer, Onyee Chan, Akshay Amaraneni, Faisal Akbar, Umar Zahid, Ali McBride, Muhammad Husnain, Ahmad Iftikhar   +8 more
openaire   +3 more sources