Results 61 to 70 of about 205,182 (367)

Outcomes following autologous hematopoietic stem cell transplant for patients with relapsed Wilms' tumor: a CIBMTR retrospective analysis. [PDF]

, 2017
Despite the marked improvement in the overall survival (OS) for patients diagnosed with Wilms' tumor (WT), the outcomes for those who experience relapse have remained disappointing.
Abdel-Azim, H, Abraham, A, Angel Diaz, M, Dandoy, C, Gale, RP, Guilcher, G, Hale, GA, Hayashi, R, Hemmer, MT, Jodele, S, Kasow, KA, Kitko, C, Le-Rademacher, J, MacMillian, ML, Malogolowkin, MH, Mehta, PA, Smith, AR, Thakar, M, Thiel, EL, Wirk, BM, Woolfrey, A   +20 more
core   +2 more sources

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation

Asia-Pacific Journal of Oncology Nursing, 2014
Objective: Stem cell transplantation is usually performed in an effort to extend the patient′s life span and to improve their quality of life. This study was conducted to determine the postoperative physiological effects experienced by patients who had ...
Sevgisun Kapucu, Yasemin Karacan
doaj   +1 more source

In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation [PDF]

Frontiers in Immunology 2014. 5:529, 2014
Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pair (DRP) undergoing stem cell transplantation (SCT). Whole exome sequencing has demonstrated extensive nucleotide sequence variation in HLA-matched DRP. Non-synonymous single
arxiv   +1 more source

Stem cell sources for regenerative medicine: the immunological point of view [PDF]

, 2018
Stem cell transplantation consists in the introduction of stem cells or derived products in a diseased organism. Because of the differentiation properties of stem cells, the goal is to replace damaged cells or tissues.
Krause, Karl-Heinz, Preynat-Seauve, Olivier   +1 more
core  

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Impact of the use of autologous stem cell transplantation at first relapse both in naïve and previously rituximab exposed follicular lymphoma patients treated in the GELA/GOELAMS FL2000 study

Haematologica, 2011
Background We analyzed detailed characteristics and salvage treatment in 175 follicular lymphoma patients from the FL2000 study who were in progression after first-line therapy with or without addition of rituximab to chemotherapy and interferon.Design ...
Steven Le Gouill, Sophie De Guibert, Lucie Planche, Pauline Brice, Jehan Dupuis, Guillaume Cartron, Achiel Van Hoof, Olivier Casasnovas, Emmanuel Gyan, Hervé Tilly, Christophe Fruchart, Eric Deconinck, Olivier Fitoussi, Lauris Gastaud, Vincent Delwail, Jean Gabarre, Rémy Gressin, Michel Blanc, Charles Foussard, Gilles Salles   +19 more
doaj   +1 more source

Successful treatment with daratumumab, lenalidomide, and dexamethasone therapy followed by autologous stem cell transplantation for newly diagnosed polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome: a case report

Journal of Medical Case Reports, 2022
Background Transplant-eligible patients with polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome are treated with induction therapy and autologous stem cell transplantation.
Ryutaro Taenaka, Sakurako Shimokawa, Ayako Katayama, Toshihiko Nagao, Teppei Obara, Naoaki Nishimura, Atsushi Tsujimoto, Kentaro Kohno, Kenichi Aoki, Ryosuke Ogawa   +9 more
doaj   +1 more source

Bayesian inference and model choice in a hidden stochastic two-compartment model of hematopoietic stem cell fate decisions [PDF]

Annals of Applied Statistics 2009, Vol. 3, No. 4, 1695-1709, 2010
Despite rapid advances in experimental cell biology, the in vivo behavior of hematopoietic stem cells (HSC) cannot be directly observed and measured. Previously we modeled feline hematopoiesis using a two-compartment hidden Markov process that had birth and emigration events in the first compartment.
arxiv   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source