Results 131 to 140 of about 4,864 (173)
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THE "AUTOLYSIN" TREATMENT FOR CANCER
Journal of the American Medical Association, 1915To the Editor: —In the Nov. 6, 1915, issue ofThe Journalthere was printed a special article by Dr. Richard Weil regarding the autolysin treatment of cancer. In this article Dr. Weil attempts to analyze the situation respecting autolysin, the method of its introduction in the General Memorial Hospital and the nature of the patients who were treated in ...
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A Computational Method for the Identification of Endolysins and Autolysins
Protein & Peptide Letters, 2020Background: Cell lytic enzyme is a kind of highly evolved protein, which can destroy the cell structure and kill the bacteria. Compared with antibiotics, cell lytic enzyme will not cause serious problem of drug resistance of pathogenic bacteria. Thus, the study of cell wall lytic enzymes aims at finding an efficient way for curing bacteria infectious.
Lei Xu +5 more
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Prokaryotic Autolysin Database Construction
Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics, 2017Databases are valuable resources that are capable of collecting and disseminating sizeable quantities of data with the purpose of furthering research done in that particular field. Currently, there are databases for organismal genomes and classes of proteins, but currently there is no database for bacterial autolysins in particular.
Brandon A. Saiz, Padmanabhan Mahadevan
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1980
Among the earliest knowledge about microbes is the fact that cells, suspended and incubated under unfavourable conditions for growth and anabolism, disintegrate. Indeed autolysates of yeasts and other cells were some of the earliest sources of soluble enzymes, and did trojan work in the heroic days of the investigations of intermediary carbohydrate ...
H. J. Rogers, H. R. Perkins, J. B. Ward
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Among the earliest knowledge about microbes is the fact that cells, suspended and incubated under unfavourable conditions for growth and anabolism, disintegrate. Indeed autolysates of yeasts and other cells were some of the earliest sources of soluble enzymes, and did trojan work in the heroic days of the investigations of intermediary carbohydrate ...
H. J. Rogers, H. R. Perkins, J. B. Ward
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Bacterial growth — from physical principles to autolysins
Current Opinion in Microbiology, 2023For bacteria to increase in size, they need to enzymatically expand their cell envelopes, and more concretely their peptidoglycan cell wall. A major task of growth is to increase intracellular space for the accumulation of macromolecules, notably proteins, RNA, and DNA.
Yuki, Kitahara, Sven, van Teeffelen
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Full-length structure of the major autolysin LytA
Acta Crystallographica Section D: Biological Crystallography, 2015LytA is responsible for the autolysis of manyStreptococcusspecies, including pathogens such asS. pneumoniae,S. pseudopneumoniaeandS. mitis. However, how this major autolysin achieves full activity remains unknown. Here, the full-length structure of theS. pneumoniaeLytA dimer is reported at 2.1 Å resolution. Each subunit has an N-terminal amidase domain
Yuhui Dong +2 more
exaly +5 more sources
1990
Cells of higher and lower plants are surrounded by a rigid cell wall, which is composed of elaborately intermeshed macromolecules. Growth, release and reproduction require a modification of this closely-knitted mesh-work.
S. Waffenschmidt, L. Jaenicke
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Cells of higher and lower plants are surrounded by a rigid cell wall, which is composed of elaborately intermeshed macromolecules. Growth, release and reproduction require a modification of this closely-knitted mesh-work.
S. Waffenschmidt, L. Jaenicke
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Autolysin as a fibronectin receptor on the cell surface of Clostridium perfringens
Anaerobe, 2023Clostridium perfringens causes food poisoning and gas gangrene, a serious wound-associated infection. C. perfringens cells adhere to collagen via fibronectin (Fn). We investigated whether the peptidoglycan hydrolase of C. perfringens, i.e., autolysin (Acp), is implicated in Fn binding to C.
Riyo, Aono +6 more
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Bacterial Walls, Peptidoglycan Hydrolases, Autolysins, and Autolysis
Microbial Drug Resistance, 1996ABSTRACT Knowledge of the chemistry, ultrastructure, biosynthesis, assembly, and function of bacterial cell walls has expanded enormously since the opening of this field of research approximately 40 years ago, primarily by the early work of Milton Salton.
SHOCKMAN G. D. +3 more
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Differentiation of Bacterial Autolysins by Zymogram Analysis
Analytical Biochemistry, 2001The use of zymograms in which the bacterial cell wall heteropolymer peptidoglycan is incorporated into the resolving gel of SDS-PAGE has led to the identification of various SDS stable peptidoglycan hydrolases (autolysins). To examine the specificity of autolysins with respect to O-acetylated peptidoglycan, a discontinuous SDS-PAGE system has been ...
H, Strating, A J, Clarke
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