Results 41 to 50 of about 83,409 (250)

SpectralConway: Cellular Automata Off The Grid [PDF]

open access: yes, 2010
SpectralConway is a spectral implementation of cellular automata (CA), specifically John Conway's Game of Life (GoL). The process eschews the traditional quantised grid paradigm of the CA in favour of a frequency continuum.
Tremblay, Pierre Alexandre   +2 more
core   +4 more sources

Heuristic optimization methods for linear ordering of automata [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Математика. Механика. Информатика
The rapid development of society is associated with two key areas of science and technology: methods of working with Big Data and Artificial Intelligence.
Farakhutdinov, Renat Abuhanovich
doaj   +1 more source

Nature, Artifice, and Discovery in Descartes’ Mechanical Philosophy

open access: yesPhilosophies, 2023
It is often assumed that in the collapse of the Aristotelian distinction between art and nature that results from the rise of mechanical philosophies in the early modern period, the collapse falls on the side of art.
Deborah Jean Brown
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Performance analysis of probabilistic timed automata using digital clocks [PDF]

open access: yes, 2006
Probabilistic timed automata, a variant of timed automata extended with discrete probability distributions, is a modelling formalism suitable for describing formally both nondeterministic and probabilistic aspects of real-time systems, and is amenable to
Kwiatkowska, M.   +4 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A propos the Puppeteer – Jean Vigo and the Cinema of Automata

open access: yesMise au Point, 2018
This essay focuses on two central elements of the cinema of Jean Vigo that have received little attention to date: Vigo’s use of puppets, manikins, and automata as a central part in his mise-en-scène, and Vigo’s status as a transitional film maker ...
Michael Wutz
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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