Results 51 to 60 of about 83,409 (250)

Fungi as Turing automata with oracles

open access: yesRoyal Society Open Science
In the article, we aim to understand the responses of living organisms, exemplified by mycelium, to external stimuli through the lens of a Turing machine with an oracle (oTM).
Andrew Schumann   +3 more
doaj   +1 more source

Instrumental Jawārī

open access: yesAl-'Usur al-Wusta, 2023
Female domestic slaves designated as jawārī (sing. jāriya) featured in a range of medieval Arabic sources, including treatises on the mechanical arts. They appeared, for example, as liquid-serving devices and timekeepers. Scholarship on automated jawārī,
Lamia Balafrej
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Repeat after me: the automatic labours of love

open access: yesJournal of Aesthetics & Culture, 2018
Modern romantic love is contemplated in association with industrial forms of production and labour. Attention is paid to the ways in which women are industrialisation’s automatic operatives par excellence, as well as the subjects and objects of love.
Lee Mackinnon
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

The Mechanism

open access: yesScreenworks, 2022
In The Mechanism, we follow Josefine Baark’s research journey as she seeks to unveil the global networks, games and friendships that resulted in a mechanical tableaux made in China in the 1730s and then brought to Denmark.
Josefine Baark   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

A Direct Translation from XPath to Nondeterministic Automata [PDF]

open access: yes, 2011
Since navigational aspects of XPath correspond to first-order definability, it has been proposed to use the analogy with the very successful technique of translating LTL into automata, and produce efficient translations of XPath queries into automata on ...
Leonid Libkin   +5 more
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