Results 141 to 150 of about 1,961,287 (207)

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Pathologic Characterization and Clinical Significance of Lymphovascular Invasion in Canine Thyroid Carcinomas

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT The association between lymphovascular invasion (LVI) and outcomes in dogs with thyroid carcinoma is inadequately described, and a standardized definition of LVI is lacking. This study's objectives were to histopathologically and immunohistochemically characterize LVI and to evaluate associated clinical outcomes in dogs with thyroid carcinoma.
Maureen A. Griffin, Brianna Stoyle, Allie Oakes, Brian Flesner, Jennifer A. Lenz, Darko Stefanovski, Amy C. Durham   +6 more
wiley   +1 more source

Diagnostic accuracy of supplemental three-dimensional breast ultrasound in the work-up of BI-RADS 0 screening recalls

Insights into Imaging
Objective To evaluate the diagnostic accuracy of supplemental 3D automated breast ultrasound (ABUS) in the diagnostic work-up of BI-RADS 0 recalls. We hypothesized that 3D ABUS may reduce the benign biopsy rate.
Bianca M. den Dekker, Mireille J. M. Broeders, Carla Meeuwis, Wikke Setz-Pels, Alexander Venmans, Carla H. van Gils, Ruud M. Pijnappel   +6 more
doaj   +1 more source

Patient perception of automated whole‐breast ultrasound

The Breast Journal, 2019
Brandi Smith, Stefanie Woodard, Alison L. Chetlen   +2 more
openaire   +2 more sources

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay, Saptarshi Mukerji, Bengt Kayser, Jui‐Lin Fan   +3 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Submucosal Invasion and Ulceration in Early Gastric Cancer Affect Mucosal Impedance

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives To investigate early changes in gastric cancers that are difficult to evaluate using endoscopic imaging through the assessment of mucosal impedance (MI) in endoscopic submucosal dissection (ESD) specimens. Methods In this single‐center prospective cohort study, we included patients who underwent ESD for early gastric cancer (EGC ...
Kaede Miyashiro, Yohei Sawada, Hidezumi Kikuchi, Shintaro Goto, Tadashi Yoshizawa, Saki Nakano, Taka Asari, Tatsuta Tetsuya, Daisuke Chinda, Hirotake Sakuraba   +9 more
wiley   +1 more source

The Evolution of Breast Cancer Detection: A Review of Imaging, Machine Learning, and Multimodal Strategies

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Breast cancer is still a serious problem in the world arena, where its early and prompt detection is the most important factor in improving patient prognosis and survival. The use of traditional diagnostic techniques, such as imaging (e.g., mammography and ultrasound) and subsequent histopathological examination, is the mainstay, which ...
Likhon Chandra Sarkar, Farida Siddiqi Prity, Farhad Hussain, Anup Talukder, Mirza Raquib, Sharmina Rahman, MD Jiabul Hoque   +6 more
wiley   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

Liquid Biopsy and Multi‐Cancer Early Detection Tests for Cancer Screening: A Scoping Review

Clinical Genetics, Volume 110, Issue 6, Page 647-685, December 2026.
There is a large body of evidence on liquid biopsy and multi‐cancer detection tests for cancer screening. Most studies addressed test performance outcomes, while fewer addressed clinical outcomes, implementation, and cost‐effectiveness. No studies evaluated cancer mortality.
Tessa Robinson, Marian Saab, Lily Thao Nguyen, Pooja Kochar, Olivia Meggetto, Jill Tinmouth, Meghan J. Walker   +6 more
wiley   +1 more source